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Dtk Protein, Mouse, Recombinant (mFc)

Dtk Protein, Mouse, Recombinant (mFc)

产品编号 TMPJ-01018
别名: TK19-2, Tyrosine-protein kinase RSE, Etk2/tyro3, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase TIF, Tyro3, Tyrosine-protein kinase DTK

Dtk Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number is P55144.

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Dtk Protein, Mouse, Recombinant (mFc)
规格 价格/CNY 货期 数量
10 μg ¥ 380 5日内发货
50 μg ¥ 820 5日内发货
500 μg ¥ 5,130 5日内发货
1 mg ¥ 8,300 5日内发货
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产品目录号及名称: Dtk Protein, Mouse, Recombinant (mFc) (TMPJ-01018)
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产品描述 Dtk Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with C-mFc tag. The predicted molecular weight is 60-90 KDa and the accession number is P55144.
种属 Mouse
表达系统 HEK293 Cells
标签 C-mFc
蛋白编号 P55144
别名 TK19-2, Tyrosine-protein kinase RSE, Etk2/tyro3, Tyrosine-protein kinase receptor TYRO3, Tyrosine-protein kinase TIF, Tyro3, Tyrosine-protein kinase DTK
氨基酸序列 Ala31-Ser418
蛋白构建 Ala31-Ser418
分子量 60-90 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted proteinsolutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Dtk, also called Tyro3, belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3, Axl, and Mer. These receptors share a characteristic molecular structure of two immunoglobulin-like and two fibronectin type III repeats and have been best characterized for their roles in immune regulation, fertility, thrombosis and phagocytosis. Gas6 and protein S have been identified as ligands for these receptors. Gas6 binding induces tyrosine phosphorylation and downstream signaling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Tyro3 and Axl play important regulatory roles in a variety of tissues, including the central nervous, reproductive, immune, and vascular systems. Tyro3 is widely expressed during embryonic development and preferentially expressed during neurogenesis in the central nervous system.

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Keywords

Dtk Protein, Mouse, Recombinant (mFc) TK19-2 Tyrosine-protein kinase RSE Etk2/tyro3 Tyrosine-protein kinase receptor TYRO3 Tyrosine-protein kinase TIF Tyro3 Tyrosine-protein kinase DTK recombinant recombinant-proteins proteins protein

 

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