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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-IKK gamma Antibody (9Q615)

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货号 TMAB-07585

Anti-IKK gamma Antibody (9Q615) 是一种 Rabbit 抗体，靶向 IKK gamma。Anti-IKK gamma Antibody (9Q615) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

Anti-IKK gamma Antibody (9Q615)

Anti-IKK gamma Antibody (9Q615)

一键复制产品信息
Rating icon 还可以
货号 TMAB-07585

Anti-IKK gamma Antibody (9Q615) 是一种 Rabbit 抗体，靶向 IKK gamma。Anti-IKK gamma Antibody (9Q615) 可用于 WB,IHC-P,IHC-Fr,IF,FCM。

规格价格库存数量
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,490
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

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产品描述
Anti-IKK gamma Antibody (9Q615) is a Rabbit antibody targeting IKK gamma. Anti-IKK gamma Antibody (9Q615) can be used in WB,IHC-P,IHC-Fr,IF,FCM.
Ig Type
IgG
克隆号
9Q615
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIFFCM
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Note=Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress.
组织特异性Heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Pro inflammatory cytokines activate the transcription factor NF kappa B by stimulating the activity of a protein kinase that phosphorylates Ikappa B, an inhibitor of NF kappa B, at sites that trigger its ubiquitination and degradation. A large, cytokine responsive Ikappa B kinase (IKK) complex has been purified and the genes encoding 2 of its subunits have been cloned. These subunits, IKK alpha and Ikk beta, are protein kinases whose function is needed for NF kappa B activation by pro inflammatory stimuli. IKK is composed of similar amounts of IKK alpha, Ikk beta, which are differentially processed forms of a third subunit, IKK gamma. IKK gamma interacts preferentially with IKK beta and is required for the activation of the IKK complex.
抗原信息
免疫原
Recombinant Protein: human IKK gamma protein
抗原种属
Human
基因名称
IKBKG
基因ID
8517
蛋白名称
NF-kappa-B essential modulator
Uniprot ID
Q9Y6K9
功能
Regulatory subunit of the IKK core complex which phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Its binding to scaffolding polyubiquitin seems to play a role in IKK activation by multiple signaling receptor pathways. Also considered to be a mediator for TAX activation of NF-kappa-B. Could be implicated in NF-kappa-B-mediated protection from cytokine toxicity. Involved in TLR3- and IFIH1-mediated antiviral innate response; this function requires 'Lys-27'-linked polyubiquitination.
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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