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Anti-Phospho-MAPT (Ser396) Antibody (4F595)

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Anti-Phospho-MAPT (Ser396) Antibody (4F595)
产品编号 TMAC-03279
别名 p-MAPT (Ser396), p-MAPT (S396), MAPT (p-Ser396), MAPT (p-S396)

Anti-Phospho-MAPT (S396) Antibody (4F595) 是一种 Rabbit 抗体,靶向 Phospho-MAPT (S396)。Anti-Phospho-MAPT (S396) Antibody (4F595) 可用于 WB,ICC/IF,IHC。

Anti-Phospho-MAPT (Ser396) Antibody (4F595)

Anti-Phospho-MAPT (Ser396) Antibody (4F595)

Rating icon 还可以
Anti-Phospho-MAPT (Ser396) Antibody (4F595)
产品编号 TMAC-03279 别名 p-MAPT (Ser396), p-MAPT (S396), MAPT (p-Ser396), MAPT (p-S396)

Anti-Phospho-MAPT (S396) Antibody (4F595) 是一种 Rabbit 抗体,靶向 Phospho-MAPT (S396)。Anti-Phospho-MAPT (S396) Antibody (4F595) 可用于 WB,ICC/IF,IHC。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MAPT (Ser396) Antibody (4F595) 是一种 Rabbit 抗体,靶向 Phospho-MAPT (Ser396)。Anti-Phospho-MAPT (Ser396) Antibody (4F595) 可用于 WB,ICC/IF,IHC。
别名p-MAPT (Ser396), p-MAPT (S396), MAPT (p-Ser396), MAPT (p-S396)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. All lanes use the Antibody at 1:4K dilution for 1 hour at room temperature.
2. Western blot analysis of Phospho-Tau (S396) expression in (1) SH-SY5Y cell lysate treated with AP; (2) SH-SY5Y cell lysate.
3. Immunohistochemical analysis of paraffin-embedded human breast carcinoma, using Phospho-Tau (S396) Antibody.
4. All lanes use the Antibody at 1:400 dilution for 1 hour at room temperature.
应用
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Tau, also known as MAPT (microtubule-associated protein tau), MAPTL, MTBT1 or TAU, is a 758 amino acid protein that localizes to the cytoplasm, as well as to the cytoskeleton and the cell membrane, and contains four Tau/MAP repeats. Expressed in neuronal tissue and existing as multiple alternatively spliced isoforms, Tau functions to promote microtubule assembly and stability and is thought to be involved in the maintenance of neuronal polarity. Tau may also link microtubules with neural plasma membrane components and, in addition to its role in microtubule stability, is also necessary for cytoskeletal plasticity. Tau is highly subject to a variety of post-translational modifications, including phosphorylation on serine and threonine residues, polyubiquitination (and subsequent proteasomal degradation) and glycation of specific Tau isoforms. Defects in the gene encoding Tau are associated with Alzheimers disease, pallido-ponto-nigral degeneration (PPND), corticobasal degeneration (CBD) and progressive supranuclear palsy (PSP).
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
A synthesized phosphopeptide: human Tau around the phosphorylation site of Ser396
抗原种属
human
Uniprot ID
化学信息
分子量Theoretical: 80 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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