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Complement Factor D/CFD Protein, Human, Recombinant (hFc)

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Complement Factor D/CFD Protein, Human, Recombinant (hFc)

产品编号 TMPK-00755

Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 51.2 kDa and the accession number is P00746-1.

Complement Factor D/CFD Protein, Human, Recombinant (hFc)

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产品编号 TMPK-00755

规格	价格	库存
5 μg	¥ 358	6-8日内发货
10 μg	¥ 573	6-8日内发货
20 μg	¥ 938	5日内发货
50 μg	¥ 1,830	5日内发货
100 μg	¥ 3,100	5日内发货
200 μg	¥ 5,620	5日内发货
500 μg	¥ 12,400	5日内发货

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产品信息

生物活性	Immobilized Human Complement Factor D, hFc Tag at 2μg/ml (100μl/Well) on the plate. Dose response curve for Biotinylated Anti-Complement Factor D Antibody, hFc Tag with the EC50 of 33.5ng/ml determined by ELISA.
产品描述	Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium. Complement Factor D/CFD Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 51.2 kDa and the accession number is P00746-1.
种属	Human
表达系统	HEK293 Cells
标签	C-hFc
蛋白编号	P00746-1
别名	PFD,FACTOR D,EC 3.4.21.46,EC 3.4.21,DF,Complement factor D,CFD,C3 convertase activator,AMBP-1,ADN,Adipsin
蛋白构建	Ile26-Ala253
蛋白纯度	> 95% as determined by Tris-Bis PAGE
分子量	51.2 kDa (predicted). Due to glycosylation, the protein migrates to 52-60 kDa based on Tris-Bis PAGE result.
内毒素	< 1 EU/μg by the LAL method.
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.
运输方式	In general, Lyophilized powders are shipping with blue ice.
研究背景	Complement factor D is a serine protease essential for the activation of the alternative pathway and is expressed in the kidney, adipocytes, and macrophages. Factor D is found at relatively high levels in glomeruli suggesting that this component of the complement cascade could influence renal pathophysiology.Complement factor D or alternative pathway activation is needed to prevent spontaneous accumulation of C3 and IgM deposits within the mesangium.