IL-1RAPL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is P59823.
生物活性 | Measured by its ability to bind biotinylated human IL1α in functional ELISA. |
产品描述 | IL-1RAPL1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65 kDa and the accession number is P59823. |
种属 | Mouse |
表达系统 | HEK293 Cells |
标签 | C-hFc |
蛋白编号 | P59823 |
别名 | 6330532G10Rik, C030039N24, IL1RAPL, IL1R8, MRX34, OPHN4, TIGIRR-2, interleukin 1 receptor accessory protein-like 1 |
蛋白构建 | The Mouse IL1RAPL1 (P59823) extracellular domain (Met 1-Thr 357) was fused with the Fc region of Human IgG1 at the C-terminus. |
蛋白纯度 | > 95 % as determined by SDS-PAGE |
分子量 | 65 kDa (predicted) |
内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) is a member of the interleukin-1 receptor family. The protein structurally comprises three extracellular immunoglobulin domains, which presumably mediate binding of an as yet unidentified ligand, a transmembrane region, and an intracellular domain, which is likely to enable signaling via the NFkB pathway. The means of signaling is almost certain to be identical to that used by the IL1R family and the more distally related Toll protein. L1RAPL1 protein physically interacts via its 150 aa C-terminal domain with neuronal calcium sensor-1 (NCS-1), a protein widely expressed in neurons and the related chromaffin and PC12 cells. IL1RAPL1 is an integral membrane protein responsible for a nonsyndromic form of mental retardation (MR). It is suggested to affect the human cognitive ability to some extent, especially the memory and concentration capability. |
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IL-1RAPL1 Protein, Mouse, Recombinant (hFc) 6330532G10Rik C030039N24 MRX 34 IL1RAPL OPHN-4 MRX-34 IL1R8 OPHN 4 MRX34 OPHN4 TIGIRR 2 TIGIRR-2 interleukin 1 receptor accessory protein-like 1 TIGIRR2 recombinant recombinant-proteins proteins protein