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CALM1 Protein, Human, Recombinant

CALM1 Protein, Human, Recombinant

产品编号 TMPJ-00029
别名: Calmodulin, CAMIII, CAMC, CALM, CALML2, CALM2, CAM2, CALM3, CAM1, CAM3, CaM, CAMB, CALM1

Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+, Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small, highly conserved protein that is 148 amino acids long. The protein has two approximately symmetrical globular domains each containing a pair of EF-hand motifs (the N- and C-domain) separated by a flexible linker region for a total of four Ca2+ binding sites. Calmodulin mediates many crucial processes such as inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes, but it is always found intracellularly.

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CALM1 Protein, Human, Recombinant
规格 价格/CNY 货期 数量
10 μg ¥ 700 5日内发货
50 μg ¥ 1,970 5日内发货
500 μg ¥ 9,890 5日内发货
1 mg ¥ 12,600 5日内发货
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产品目录号及名称: CALM1 Protein, Human, Recombinant (TMPJ-00029)
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产品性质
产品描述 Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+, Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small, highly conserved protein that is 148 amino acids long. The protein has two approximately symmetrical globular domains each containing a pair of EF-hand motifs (the N- and C-domain) separated by a flexible linker region for a total of four Ca2+ binding sites. Calmodulin mediates many crucial processes such as inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes, but it is always found intracellularly.
种属 Human
表达系统 E. coli
标签 Tag Free
蛋白编号 P0DP23
别名 Calmodulin, CAMIII, CAMC, CALM, CALML2, CALM2, CAM2, CALM3, CAM1, CAM3, CaM, CAMB, CALM1
氨基酸序列 Met1-Lys149
蛋白构建 Met1-Lys149
蛋白纯度 Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
分子量 16 KDa (reducing condition)
内毒素 < 0.1 ng/µg (1 EU/µg) as determined by LAL test.
缓冲液 Lyophilized from a solution filtered through a 0.22 μm filter, containing 50 mM NH4HCO3, pH 8.0.
复溶方法 Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

运输方式

In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice.

研究背景 Calmodulin (CaM) is a multifunctional intermediate calcium-binding messenger protein expressed in all eukaryotic cells. It is an intracellular target of the secondary messenger Ca2+, and the binding of Ca2+ is required for the activation of Calmodulin. Once bound to Ca2+, Calmodulin acts as part of a calcium signal transduction pathway by modifying its interactions with various target proteins such as kinases or phosphatases. Calmodulin is a small, highly conserved protein that is 148 amino acids long. The protein has two approximately symmetrical globular domains each containing a pair of EF-hand motifs (the N- and C-domain) separated by a flexible linker region for a total of four Ca2+ binding sites. Calmodulin mediates many crucial processes such as inflammation, metabolism, apoptosis, smooth muscle contraction, intracellular movement, short-term and long-term memory, and the immune response. Calmodulin is expressed in many cell types and can have different subcellular locations, including the cytoplasm, within organelles, or associated with the plasma or organelle membranes, but it is always found intracellularly.

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Keywords

CALM1 Protein, Human, Recombinant CALML 2 Calmodulin CAM 2 CAMIII CAM 1 CAMC CALM CALML2 CALM2 CAM2 CALM3 CAM1 CAM3 CALM 3 CAM-1 CAM-2 CALML-2 CALM 2 CALM-3 CaM CAMB CALM 1 CAM 3 CAM-3 CALM1 CALM-1 CALM-2 recombinant recombinant-proteins proteins protein

 

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