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别名 NKSF2, NKSF, interleukin 12B, IMD29, IMD28, IL-12B, IL12 p40, CLMF2, CLMF
Anti-IL-12B Antibody (1Q82) 是一种抗体,靶向 IL-12B。Anti-IL-12B Antibody (1Q82) 可用于 ELISA,FCM。
Anti-IL-12B Antibody (1Q82) 是一种抗体,靶向 IL-12B。Anti-IL-12B Antibody (1Q82) 可用于 ELISA,FCM。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,305 | 5日内发货 | |
| 100 μL | ¥ 2,180 | 5日内发货 |
| 产品描述 | Anti-IL-12B Antibody (1Q82) is an antibody targeting IL-12B. Anti-IL-12B Antibody (1Q82) can be used in ELISA,FCM. |
| 别名 | NKSF2, NKSF, interleukin 12B, IMD29, IMD28, IL-12B, IL12 p40, CLMF2, CLMF |
| Ig Type | Rabbit IgG |
| 克隆号 | 1Q82 |
| 交叉反应 | Human |
| 验证活性 | Overlay Peak curve showing A549 cells stained with TMAH-00609 (red line) at 1:50. The cells were fixed in 4% formaldehyde and permeated by 0.2% TritonX-100. Then 10% normal goat serum to block non-specific protein-protein interactions followed by the antibody (1µg/1*10^6 cells) for 45min at 4°C. The secondary antibody used was FITC-conjugated Goat Anti-rabbit IgG(H+L) at 1:200 dilution for 35min at 4°C.Control antibody (green line) was rabbit IgG (1µg/1*10^6 cells) used under the same conditions. Acquisition of >10,000 events was performed. |
| 应用 | ELISAFCM |
| 推荐剂量 | FCM:1:50-1:200. |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | Secreted. |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human IL12B |
| 抗原种属 | Human |
| 基因名称 | IL12B |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Cancer, Immunology |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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