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Anti-B2M/beta 2-Microglobulin Antibody-APC (9P155)
还可以产品编号 TMAY-02180A
Anti-B2M/beta 2-Microglobulin Antibody-APC (9P155) 是一种 APC-conjugated Mouse 抗体，靶向 B2M/beta 2-Microglobulin。Anti-B2M/beta 2-Microglobulin Antibody-APC (9P155) 可用于 FCM。
Anti-B2M/beta 2-Microglobulin Antibody-APC (9P155)
Anti-B2M/beta 2-Microglobulin Antibody-APC (9P155)
还可以产品编号 TMAY-02180A
Anti-B2M/beta 2-Microglobulin Antibody-APC (9P155) 是一种 APC-conjugated Mouse 抗体，靶向 B2M/beta 2-Microglobulin。Anti-B2M/beta 2-Microglobulin Antibody-APC (9P155) 可用于 FCM。
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抗原信息
| 产品描述 | Anti-B2M/beta 2-Microglobulin Antibody-APC (9P155) is a APC-conjugated Mouse antibody targeting B2M/beta 2-Microglobulin. Anti-B2M/beta 2-Microglobulin Antibody-APC (9P155) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 9P155 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human B2M / Beta-2-microglobulin expression on human whole blood lymphocytes. Cells were stained with APC-conjugated anti-Human B2M / Beta-2-microglobulin. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 2 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Beta-2 microglobulin/B2M (rh Beta-2 microglobulin/B2M; TMPY-01686; NP_004039.1; Met1-Met119) and conjugated with APC under optimum conditions, the unreacted APC was removed. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
| 研究背景 | B2M, also known as β2-Microglobulin or CDABP0092, is a component of MHC class I molecules found expression in all nucleated cells (excludes red blood cells). The major function of MHC class I moleculesis is to display fragments of proteins from within the cell to T-cells and cells containing foreign proteins will be attacked. B2M (β2-Microglobulin) is a low molecular weight protein. It was demonstrated that B2M (β2-Microglobulin) was localized in the membranes of nucleated cells and was found to be associated with HL-A antigens. B2M (β2- Microglobulin) is present in free form in various body fluids and as a subunit of histocompatibility antigens on cell surfaces lateral to the α3 chain. Unlike α3, β2 has no transmembrane region. Directly above β2 lies the α1 chain, which itself is lateral to the α2. In the absence of B2M (β2 microglobulin), very limited amounts of MHC class I (classical and non-classical) molecules can be detected on the surface. In the absence of MHC class I, CD8 T cells, a subset of T cells involved in the development of acquired immunity cannot develop. Low levels of B2M (β2 microglobulin) can indicate non-progression of HIV. |
| 偶联 | APC |
| 其他可选修饰符 | Unconjugated/FITC/PE |
| 可提供抗体种类 | 4 |
| 免疫原 | Recombinant Human Beta-2 microglobulin/B2M Protein (TMPY-01686) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
| 运输方式 | Shipping with blue ice. |
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