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Anti-CCL20 Antibody (2P759)
还可以产品编号 TMAY-00889
Anti-CCL20 Antibody (2P759) 是一种 Mouse 抗体，靶向 CCL20。Anti-CCL20 Antibody (2P759) 可用于 ELISA,ELISA(Det)。
Anti-CCL20 Antibody (2P759)
Anti-CCL20 Antibody (2P759)
还可以产品编号 TMAY-00889
Anti-CCL20 Antibody (2P759) 是一种 Mouse 抗体，靶向 CCL20。Anti-CCL20 Antibody (2P759) 可用于 ELISA,ELISA(Det)。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-CCL20 Antibody (2P759) is a Mouse antibody targeting CCL20. Anti-CCL20 Antibody (2P759) can be used in ELISA,ELISA(Det). |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 2P759 |
| 交叉反应 | Human |
| 应用 | ELISA,ELISA(Det) |
| 推荐剂量 | ELISA: 1:1000-1:2000; ELISA(Det): 1:1000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CCL20 / MIP-3 alpha / MIP3A (rh CCL20 / MIP-3 alpha / MIP3A; TMPY-03935; P78556-1; Ala27-Met96). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Chemokine (C-C motif) ligand 20 (CCL20) or liver activation regulated chemokine (LARC) or Macrophage Inflammatory Protein-3 (MIP3A) is a small cytokine belonging to the CC chemokine family that attracts immature dendritic cells and memory T lymphocytes, both expressing CCR6. Depending on the cell type, this chemokine was found to be inducible by cytokines (IL-1beta) and by bacterial, viral, or plant products (including LPS, dsRNA, and PMA). MIP3A / CCL20 is Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels of MIP3A / CCL20 has been seen in thymus, prostate, testis, small intestine and colon. As a chemotactic factor, MIP3A / CCL20 attracts lymphocytes and, slightly, neutrophils, but not monocytes. This chemokine may Inhibit proliferation of myeloid progenitors in colony formation assays and it may be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. Its C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Chemokine CCL20 was shown to play a role in colorectal cancer (CRC) pathogenesis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human CCL20 / MIP-3 alpha / MIP3A Protein (TMPY-03935) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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