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Anti-EML4 Polyclonal Antibody

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货号 TMAB-05556

Anti-EML4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EML4。Anti-EML4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-EML4 Polyclonal Antibody

Anti-EML4 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-05556

Anti-EML4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EML4。Anti-EML4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-EML4 Polyclonal Antibody is a Rabbit antibody targeting EML4. Anti-EML4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Human (predicted:Mouse,Rat)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm, cytoskeleton (Potential).
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Microtubules are components of the Actin cytoskeleton that play crucial roles in cell morphogenesis, cell motility, spindle formation and chromosome movements. Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules. EML4 (Echinoderm microtubule-associated protein-like 4), also known as EMAPL4, ELP120, C2orf2 or ROPP120, is a 981 amino acid cytoplasmic protein that contains nine WD repeats. Expressed at high levels during mitosis, EML4 is thought to modify the assembly dynamics of microtubules, specifically altering microtubules to become longer and more flexible. Due to a chromosomal inversion with chromosome 2p, EML4 may exist as a fusion protein with ALK (anaplastic lymphoma receptor tyrosine kinase), producing an EML4-ALK fusion complex that plays a role in the pathogenesis of lung cancer.
抗原信息
免疫原
KLH conjugated synthetic peptide: human EML4-ALK fusion protein(EML4)
抗原种属
Human
基因名称
EML4
基因ID
蛋白名称
Echinoderm microtubule-associated protein-like 4
Uniprot ID
功能
May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity).
化学信息
分子量Theoretical: 109 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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