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Anti-EML4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EML4。Anti-EML4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
Anti-EML4 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 EML4。Anti-EML4 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,170 | 5日内发货 | |
| 100 μL | ¥ 1,970 | 5日内发货 | |
| 200 μL | ¥ 2,785 | 5日内发货 |
| 产品描述 | Anti-EML4 Polyclonal Antibody is a Rabbit antibody targeting EML4. Anti-EML4 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF. |
| Ig Type | IgG |
| 反应种属 | Human (predicted:Mouse,Rat) |
| 应用 | IHC-PIHC-FrIF |
| 推荐剂量 | IHC-P: 1:400-800; IHC-Fr: 1:400-800; IF: 1:100-500 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cytoplasm, cytoskeleton (Potential). |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | Microtubules are components of the Actin cytoskeleton that play crucial roles in cell morphogenesis, cell motility, spindle formation and chromosome movements. Echinoderm microtubule-associated (EML) proteins function to modify the assembly dynamics of microtubules. EML4 (Echinoderm microtubule-associated protein-like 4), also known as EMAPL4, ELP120, C2orf2 or ROPP120, is a 981 amino acid cytoplasmic protein that contains nine WD repeats. Expressed at high levels during mitosis, EML4 is thought to modify the assembly dynamics of microtubules, specifically altering microtubules to become longer and more flexible. Due to a chromosomal inversion with chromosome 2p, EML4 may exist as a fusion protein with ALK (anaplastic lymphoma receptor tyrosine kinase), producing an EML4-ALK fusion complex that plays a role in the pathogenesis of lung cancer. |
| 免疫原 | KLH conjugated synthetic peptide: human EML4-ALK fusion protein(EML4) |
| 抗原种属 | Human |
| 基因名称 | EML4 |
| 基因ID | |
| 蛋白名称 | Echinoderm microtubule-associated protein-like 4 |
| Uniprot ID | |
| 功能 | May modify the assembly dynamics of microtubules, such that microtubules are slightly longer, but more dynamic (By similarity). |
| 分子量 | Theoretical: 109 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |