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Anti-Phospho-RPA2 (T21) Antibody (1G657) 是一种 Rabbit 抗体,靶向 Phospho-RPA2 (T21)。Anti-Phospho-RPA2 (T21) Antibody (1G657) 可用于 WB,IP。
Anti-Phospho-RPA2 (T21) Antibody (1G657) 是一种 Rabbit 抗体,靶向 Phospho-RPA2 (T21)。Anti-Phospho-RPA2 (T21) Antibody (1G657) 可用于 WB,IP。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-Phospho-RPA2 (Thr21) Antibody (1G657) 是一种 Rabbit 抗体,靶向 Phospho-RPA2 (Thr21)。Anti-Phospho-RPA2 (Thr21) Antibody (1G657) 可用于 WB,IP。 |
别名 | RPA2 (p-Thr21), RPA2 (p-T21), p-RPA2 (Thr21), p-RPA2 (T21), Phospho-RPA2 (T21) |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
验证活性 | 1. Western blot analysis of RPA32/RPA2 (phospho T21) on Hela cells lysates using anti-RPA32/RPA2 (phospho T21) antibody at 1/1,000 dilution. |
应用 | |
推荐剂量 | WB: 1:1000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Hybridoma Monoclonal Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, mitochondria, phages and viruses. Replication protein A (RPA), a highly conserved eukaryotic protein, is a heterotrimeric SSB. RPA plays an important role in DNA replication, recombination and repair. The binding of human RPA (hRPA) to DNA involves molecular polarity in which initial hRPA binding occurs on the 5' side of a ssDNA substrate and then extends in the 3' direction to create a stably bound hRPA. RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The C-terminus of RPA 32 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, RPA 32 binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA 32 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3. |
偶联 | Unconjugated |
其他可选修饰符 | Phospho |
免疫原 | Synthetic phospho-peptide corresponding to residues surrounding Thr21 of human RPA32/RPA2 |
抗原种属 | human |
Uniprot ID |
分子量 | Theoretical: 32 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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