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Anti-Phospho-RPA2 (Thr21) Antibody (1G657)

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Anti-Phospho-RPA2 (Thr21) Antibody (1G657)
产品编号 TMAC-03627
别名 RPA2 (p-Thr21), RPA2 (p-T21), p-RPA2 (Thr21), p-RPA2 (T21), Phospho-RPA2 (T21)

Anti-Phospho-RPA2 (T21) Antibody (1G657) 是一种 Rabbit 抗体,靶向 Phospho-RPA2 (T21)。Anti-Phospho-RPA2 (T21) Antibody (1G657) 可用于 WB,IP。

Anti-Phospho-RPA2 (Thr21) Antibody (1G657)

Anti-Phospho-RPA2 (Thr21) Antibody (1G657)

Rating icon 还可以
Anti-Phospho-RPA2 (Thr21) Antibody (1G657)
产品编号 TMAC-03627 别名 RPA2 (p-Thr21), RPA2 (p-T21), p-RPA2 (Thr21), p-RPA2 (T21), Phospho-RPA2 (T21)

Anti-Phospho-RPA2 (T21) Antibody (1G657) 是一种 Rabbit 抗体,靶向 Phospho-RPA2 (T21)。Anti-Phospho-RPA2 (T21) Antibody (1G657) 可用于 WB,IP。

规格价格库存数量
50 μL
¥ 1,480
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-RPA2 (Thr21) Antibody (1G657) 是一种 Rabbit 抗体,靶向 Phospho-RPA2 (Thr21)。Anti-Phospho-RPA2 (Thr21) Antibody (1G657) 可用于 WB,IP。
别名RPA2 (p-Thr21), RPA2 (p-T21), p-RPA2 (Thr21), p-RPA2 (T21), Phospho-RPA2 (T21)
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of RPA32/RPA2 (phospho T21) on Hela cells lysates using anti-RPA32/RPA2 (phospho T21) antibody at 1/1,000 dilution.
应用
推荐剂量
WB: 1:1000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Hybridoma Monoclonal Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景The single-stranded-DNA-binding proteins (SSBs) are essential for DNA function in prokaryotic and eukaryotic cells, mitochondria, phages and viruses. Replication protein A (RPA), a highly conserved eukaryotic protein, is a heterotrimeric SSB. RPA plays an important role in DNA replication, recombination and repair. The binding of human RPA (hRPA) to DNA involves molecular polarity in which initial hRPA binding occurs on the 5' side of a ssDNA substrate and then extends in the 3' direction to create a stably bound hRPA. RPA is a major damage-recognition protein involved in the early stages of nucleotide excision repair. It can also play a role in telomere maintenance. The C-terminus of RPA 32 can specfically intereact with the DNA repair enzyme UNG2 and repair factors XPA and Rad52, each of which functions in a different repair pathway. In addition, RPA 32 binds specifically to the SH2 domain of Stat3 in vivo, and overexpression of RPA 32 corresponds to the augmented growth factor-stimulated tyrosine phosphorylation and transcription activities of Stat3.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Synthetic phospho-peptide corresponding to residues surrounding Thr21 of human RPA32/RPA2
抗原种属
human
Uniprot ID
化学信息
分子量Theoretical: 32 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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