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顶部生物活性储存和溶解信息计算器

Anti-Caspase 5 Antibody (3R203)

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Anti-Caspase 5 Antibody (3R203)
产品编号 TMAC-00571
别名 TY protease, TY, MGC141966, ICH3 protease, ICH3, ICH 3 protease, ICH 3, ICERELIII, ICEREL III, ICE(rel)III, ICE(rel) III, ICE, Caspase-5 subunit p20, Caspase-5, Caspase5, caspase 5 apoptosis related cysteine protease, Caspase 5 apoptosis related cysteine peptidase, CASP5, CASP 5, Apoptosis related cysteine protease

Anti-Caspase 5 Antibody (3R203) 是一种 Rabbit 抗体，靶向 Caspase 5。Anti-Caspase 5 Antibody (3R203) 可用于 WB,ICC/IF,IHC,IP。

Anti-Caspase 5 Antibody (3R203)

Anti-Caspase 5 Antibody (3R203)

Rating icon 还可以
Anti-Caspase 5 Antibody (3R203)
产品编号 TMAC-00571 别名 TY protease, TY, MGC141966, ICH3 protease, ICH3, ICH 3 protease, ICH 3, ICERELIII, ICEREL III, ICE(rel)III, ICE(rel) III, ICE, Caspase-5 subunit p20, Caspase-5, Caspase5, caspase 5 apoptosis related cysteine protease, Caspase 5 apoptosis related cysteine peptidase, CASP5, CASP 5, Apoptosis related cysteine protease

Anti-Caspase 5 Antibody (3R203) 是一种 Rabbit 抗体，靶向 Caspase 5。Anti-Caspase 5 Antibody (3R203) 可用于 WB,ICC/IF,IHC,IP。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,485
5日内发货
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产品介绍

生物活性
产品描述
Anti-Caspase 5 Antibody (3R203) is a Rabbit antibody targeting Caspase 5. Anti-Caspase 5 Antibody (3R203) can be used in WB,ICC/IF,IHC,IP.
别名TY protease, TY, MGC141966, ICH3 protease, ICH3, ICH 3 protease, ICH 3, ICERELIII, ICEREL III, ICE(rel)III, ICE(rel) III, ICE, Caspase-5 subunit p20, Caspase-5, Caspase5, caspase 5 apoptosis related cysteine protease, Caspase 5 apoptosis related cysteine peptidase, CASP5, CASP 5, Apoptosis related cysteine protease
Ig Type
IgG
交叉反应
Human
验证活性
1. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-Caspase 5 antibody. Counter stained with hematoxylin.
2. ICC staining Caspase 5 in A549 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Caspase 5 in Hela cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
4. ICC staining Caspase 5 in SHG-44 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
应用
WB
ICC/IF
IHC
IP
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Caspases are cysteine proteases which play important roles in the activation of cytokines and in apoptosis. The ICE subfamily of caspases comprises peptides closely related to caspase-1, which promotes maturation of interleukin 1β (IL-1β) and interleukin-18 (IL-18) by proteolytic cleavage of precursor forms to generate biologically active peptides. Both caspase-4 and caspase-5 are members of the caspase-1 subfamily, and are more closely related to each other than to other homologues. Caspase-5 (also designated ICErel-III, TY, ICH-3 and caspase-12 in mouse), can cleave its own precursor, an activity that requires the cysteine 245 residue. Frameshift mutations in caspase-5 have been identified in MMP tumors of the endometrium, colon, and stomach, indicating the caspase-5 may be a new target gene in the microsatellite mutator pathway for cancer. The human caspase 5 gene maps to chromosome 11q22.2-q22.3 and encodes a protein whose expression is barely detectable in most tissues except brain, with highest expression levels being found in lung, liver and skeletal muscle.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P51878
化学信息
分子量Theoretical: 47 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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