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Anti-MAP1D Antibody (8D880)

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Anti-MAP1D Antibody (8D880)
产品编号 TMAY-01282
别名 methionyl aminopeptidase type 1D (mitochondrial), Metap1l, MetAP 1D, MAP1D, MAP 1D

Anti-MAP1D Antibody (8D880) 是一种 Mouse 抗体,靶向 MAP1D。Anti-MAP1D Antibody (8D880) 可用于 ELISA。

Anti-MAP1D Antibody (8D880)
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Anti-MAP1D Antibody (8D880)

Rating icon 还可以
Anti-MAP1D Antibody (8D880)
产品编号 TMAY-01282 别名 methionyl aminopeptidase type 1D (mitochondrial), Metap1l, MetAP 1D, MAP1D, MAP 1D

Anti-MAP1D Antibody (8D880) 是一种 Mouse 抗体,靶向 MAP1D。Anti-MAP1D Antibody (8D880) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 1,679
5日内发货
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产品介绍

生物活性
产品描述
Anti-MAP1D Antibody (8D880) is a Mouse antibody targeting MAP1D. Anti-MAP1D Antibody (8D880) can be used in ELISA.
别名methionyl aminopeptidase type 1D (mitochondrial), Metap1l, MetAP 1D, MAP1D, MAP 1D
Ig Type
Mouse IgG1
克隆号
8D880
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:1000-1:2000
抗体种类
Monoclonal
宿主来源Mouse
构建方式This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MAP1D (rh MAP1D; TMPY-01344; NP_954697.1; Arg 44-Ala 335). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Methionine aminopeptidase 1D, also known as MAP1D, is a member of the peptidase M24A family. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. The enzymes that catalyze this reaction are called Methionine aminopeptidases (MAPs). MAP1D is overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level). Downregulation of MAP1D expression by shRNA in HCT-116 colon carcinoma cells reduces anchorage-independent growth in soft agar. MAP1D binds two cobalt ions per subunit. The true nature of the physiological cofactor is under debate. MAP1D is also active with zinc, manganese, or divalent ions. MAP1D removes the amino-terminal methionine from nascent proteins. It may also play an important role in colon tumorigenesis.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Human MAP1D protein (TMPY-01344)
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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