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Anti-MAP1D Antibody (8D880)
还可以产品编号 TMAY-01282
Anti-MAP1D Antibody (8D880) 是一种 Mouse 抗体，靶向 MAP1D。Anti-MAP1D Antibody (8D880) 可用于 ELISA。
Anti-MAP1D Antibody (8D880)
Anti-MAP1D Antibody (8D880)
还可以产品编号 TMAY-01282
Anti-MAP1D Antibody (8D880) 是一种 Mouse 抗体，靶向 MAP1D。Anti-MAP1D Antibody (8D880) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-MAP1D Antibody (8D880) is a Mouse antibody targeting MAP1D. Anti-MAP1D Antibody (8D880) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 8D880 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MAP1D (rh MAP1D; TMPY-01344; NP_954697.1; Arg 44-Ala 335). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Methionine aminopeptidase 1D, also known as MAP1D, is a member of the peptidase M24A family. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. The enzymes that catalyze this reaction are called Methionine aminopeptidases (MAPs). MAP1D is overexpressed in colon cancer cell lines and colon tumors as compared to normal tissues (at protein level). Downregulation of MAP1D expression by shRNA in HCT-116 colon carcinoma cells reduces anchorage-independent growth in soft agar. MAP1D binds two cobalt ions per subunit. The true nature of the physiological cofactor is under debate. MAP1D is also active with zinc, manganese, or divalent ions. MAP1D removes the amino-terminal methionine from nascent proteins. It may also play an important role in colon tumorigenesis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human MAP1D protein (TMPY-01344) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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