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Anti-CK12 Polyclonal Antibody

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货号 TMAB-04383

Anti-CK12 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CK12。Anti-CK12 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-CK12 Polyclonal Antibody

Anti-CK12 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-04383

Anti-CK12 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 CK12。Anti-CK12 Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍


生物活性
产品描述
Anti-CK12 Polyclonal Antibody is a Rabbit antibody targeting CK12. Anti-CK12 Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Rabbit)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
组织特异性Cornea specific.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Cytokeratin 12 is a member of the intermediate filament family of proteins and is a heterotetramer of two type I and two type II keratins. Keratin 3 is specifically expressed in the corneal epithelium with family member KRT12. Cytokeratin 12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Defects in KRT3 and KRT12 are a cause of Meesmann corneal dystrophy (MCD), an autosomal dominant disease that causes fragility of the anterior corneal epithelium. Symptoms occur in adulthood and include rupture of the corneal microcysts that may lead to photophobia, contact lens intolerance and intermittent diminution of visual acuity. Defects in KRT12 are a cause of juvenile epithelial corneal dystrophy of Meesmann (MCD)
抗原信息
免疫原
KLH conjugated synthetic peptide: human CK12/Cytokeratin 12
抗原种属
Human
基因名称
KRT12
基因ID
蛋白名称
Keratin, type I cytoskeletal 12
Uniprot ID
功能
May play a unique role in maintaining the normal corneal epithelial function. Together with KRT3, essential for the maintenance of corneal epithelium integrity (By similarity).
化学信息
分子量Theoretical: 54 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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