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Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody

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产品编号 TMAC-02247
别名 p-ITCH (Y420), p-ITCH (Tyr420), ITCH (p-Y420), ITCH (p-Tyr420)

Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ITCH (Tyr420)。Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody 可用于 IHC。

Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody

Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody

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Rating icon 还可以
产品编号 TMAC-02247 别名 p-ITCH (Y420), p-ITCH (Tyr420), ITCH (p-Y420), ITCH (p-Tyr420)

Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody 是一种 Rabbit 抗体,靶向 Phospho-ITCH (Tyr420)。Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody 可用于 IHC。

规格价格库存数量
50 μL
¥ 1,485
5日内发货
100 μL
¥ 2,240
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody is a Rabbit antibody targeting Phospho-ITCH (Tyr420). Anti-Phospho-ITCH (Tyr420) Polyclonal Antibody can be used in IHC.
别名p-ITCH (Y420), p-ITCH (Tyr420), ITCH (p-Y420), ITCH (p-Tyr420)
Ig Type
IgG
交叉反应
Human,Mouse
验证活性
1. Immunohistochemical analysis of paraffin-embedded human brain tissue using ITCH (Phospho-Tyr420) antibody TMAC-02247 (left) or the same antibody preincubated with blocking peptide (right).
verifiedActivity
应用IHC
推荐剂量
IHC: 1:50-100
抗体种类
Polyclonal
宿主来源Rabbit
构建方式Polyclonal Antibody
纯化方式Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
性状Liquid
缓冲液Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
研究背景Atrophin-1 contains a polyglutamine repeat, expansion of which is responsible for dentatorubral and pallidoluysian atrophy. The protein encoded by this gene interacts with atrophin-1. This encoded protein is a closely related member of the NEDD4-like protein family. This family of proteins are E3 ubiquitin-ligase molecules and regulate key trafficking decisions, including targeting of proteins to proteosomes or lysosomes. This encoded protein contains four tandem WW domains and a HECT (homologous to the E6-associated protein carboxyl terminus) domain.
偶联与修饰
偶联
Unconjugated
其他可选修饰符
Phospho
抗原信息
免疫原
Peptide sequence around phosphorylation site of tyrosine 420(F-I-Y(p)-G-N) derived from Human ITCH
抗原种属
human
Uniprot ID
化学信息
分子量Actual: 102 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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