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MBL2 Protein, Human, Recombinant (His)

Synonyms: MBP-C, MBP1, MBL2, MBL, Mannose-Binding Protein C, Mannose-Binding Lectin, Mannan-Binding Protein, Collectin-1, COLEC1
货号 TMPJ-00136 一键复制产品信息
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Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural features: a cysteine rich amino-terminal domain, a collagen-like region, an α-helical coiled-coil neck domain and a carboxy terminal C-type Lectin or carbohydrate recognition domain (CRD). MBL homotrimerizes to form a structural unit joined by N-terminal disulfide bridges. These homotrimers further associates into oligomeric structures of up to 6 units. Whereas two forms of MBL proteins exist in rodents and other animals. Human MBL-2 is 25 kDa. Human MBL-2 is a secreted glycoprotein that is synthesized as a 248 amino acid (aa) precursor that contains a 20 aa signal sequence, a 21 aa cysteine-rich region, a 58 aa collagen-like segment and a 111 aa C-type lectin domain that binds to neutral bacterial carbohydrates.

MBL2 Protein, Human, Recombinant (His)

一键复制产品信息
Rating icon 很棒
SPR兼容缓冲液
货号 TMPJ-00136

别名 MBP-C, MBP1, MBL2, MBL, Mannose-Binding Protein C, Mannose-Binding Lectin, Mannan-Binding Protein, Collectin-1, COLEC1

Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural features: a cysteine rich amino-terminal domain, a collagen-like region, an α-helical coiled-coil neck domain and a carboxy terminal C-type Lectin or carbohydrate recognition domain (CRD). MBL homotrimerizes to form a structural unit joined by N-terminal disulfide bridges. These homotrimers further associates into oligomeric structures of up to 6 units. Whereas two forms of MBL proteins exist in rodents and other animals. Human MBL-2 is 25 kDa. Human MBL-2 is a secreted glycoprotein that is synthesized as a 248 amino acid (aa) precursor that contains a 20 aa signal sequence, a 21 aa cysteine-rich region, a 58 aa collagen-like segment and a 111 aa C-type lectin domain that binds to neutral bacterial carbohydrates.

MBL2 Protein, Human, Recombinant (His)
其他形式的 “MBL2 Protein, Human, Recombinant (His)”:
规格价格库存数量
5 μg
¥ 385
现货
10 μg
¥ 620
现货
20 μg
¥ 958
现货
50 μg
¥ 1,730
现货
100 μg
¥ 2,970
现货
200 μg
¥ 5,550
35日内发货
500 μg
¥ 12,100
35日内发货
1 mg
¥ 17,300
35日内发货
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选择批次:
纯度: Greater than 95% as determined by reducing SDS-PAGE.
颜色: 白色
性状: Lyophilized powder
资源下载: COA重组蛋白用户指南

产品介绍


生物活性
产品描述
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural features: a cysteine rich amino-terminal domain, a collagen-like region, an α-helical coiled-coil neck domain and a carboxy terminal C-type Lectin or carbohydrate recognition domain (CRD). MBL homotrimerizes to form a structural unit joined by N-terminal disulfide bridges. These homotrimers further associates into oligomeric structures of up to 6 units. Whereas two forms of MBL proteins exist in rodents and other animals. Human MBL-2 is 25 kDa. Human MBL-2 is a secreted glycoprotein that is synthesized as a 248 amino acid (aa) precursor that contains a 20 aa signal sequence, a 21 aa cysteine-rich region, a 58 aa collagen-like segment and a 111 aa C-type lectin domain that binds to neutral bacterial carbohydrates.
生物活性
Activity has not been tested. It is theoretically active, but we cannot guarantee it. If you require protein activity, we recommend choosing the eukaryotic expression version first.
研究背景
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural features: a cysteine rich amino-terminal domain, a collagen-like region, an α-helical coiled-coil neck domain and a carboxy terminal C-type Lectin or carbohydrate recognition domain (CRD). MBL homotrimerizes to form a structural unit joined by N-terminal disulfide bridges. These homotrimers further associates into oligomeric structures of up to 6 units. Whereas two forms of MBL proteins exist in rodents and other animals. Human MBL-2 is 25 kDa. Human MBL-2 is a secreted glycoprotein that is synthesized as a 248 amino acid (aa) precursor that contains a 20 aa signal sequence, a 21 aa cysteine-rich region, a 58 aa collagen-like segment and a 111 aa C-type lectin domain that binds to neutral bacterial carbohydrates.
种属
Human
表达系统
HEK293 Cells
标签
C-6xHis
蛋白编号P11226
氨基酸序列
Glu21-Ile248
蛋白构建
Glu21-Ile248
蛋白纯度
Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
MBL2 Protein, Human, Recombinant (His)
缓冲液
Lyophilized from a solution filtered through a 0.22 μm filter, containing 20 mM PB, 150 mM NaCl, 5% Threhalose, pH 7.2.
复溶方法
Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名
MBP-C, MBP1, MBL2, MBL, Mannose-Binding Protein C, Mannose-Binding Lectin, Mannan-Binding Protein, Collectin-1, COLEC1
内毒素< 0.1 ng/µg (1 EU/µg) as determined by LAL test.
化学信息
分子量31 KDa (reducing condition)
储存&溶解度
运输方式In general, lyophilized powders are shipped with blue ice, while solutions are shipped with dry ice.
存储

Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

实际储存温度请以COA为准

计算器

  • 复溶 计算器
  • 重组蛋白稀释 计算器
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剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

技术支持

请阅读 重组蛋白用户指南 了解更多具体信息.
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