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Anti-Phospho-AMPKα (Thr172) Antibody (3O988)
还可以产品编号 TMAY-01557
Anti-Phospho-AMPKα (Thr172) Antibody (3O988) 是一种 Rabbit 抗体，靶向 Phospho-AMPKα (Thr172)。Anti-Phospho-AMPKα (Thr172) Antibody (3O988) 可用于 WB。
Anti-Phospho-AMPKα (Thr172) Antibody (3O988)
Anti-Phospho-AMPKα (Thr172) Antibody (3O988)
还可以产品编号 TMAY-01557
Anti-Phospho-AMPKα (Thr172) Antibody (3O988) 是一种 Rabbit 抗体，靶向 Phospho-AMPKα (Thr172)。Anti-Phospho-AMPKα (Thr172) Antibody (3O988) 可用于 WB。
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生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Phospho-AMPKα (Thr172) Antibody (3O988) is a Rabbit antibody targeting Phospho-AMPKα (Thr172). Anti-Phospho-AMPKα (Thr172) Antibody (3O988) can be used in WB. |
| Ig Type | Monoclonal Rabbit IgG |
| 克隆号 | 3O988 |
| 交叉反应 | Human; Predicted to React with:Species predicted to react based on 100% sequence homology: Mouse, Cynomolgus, Pig |
| 验证活性 | Western blot analysis of extracts from Rat brain, untreated (line A); treated with λ-phosphatase (line B) using Phospho-AMPKα (Thr172) rabbit monoclonal Antibody at 1:2000 dilution. |
| 应用 | WB |
| 推荐剂量 | WB: 1:2000-1:20000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the residues around (Thr172) of Human Phospho-AMPKα. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 10 mM sodium HEPES, 150 mM NaCl, 100 μg/mL BSA, 50% glycerol, pH 7.5 |
| 研究背景 | The PRKAA1 gene encodes the catalytic alpha-subunit of 5' AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor that maintains energy homeostasis within the cell and is activated when the AMP/ATP ratio increases. Moreover, AMPK has been shown to be involved in inhibiting tumour growth and metastasis, and has also been implicated in the pathology of neurodegenerative and cardiac disorders. All 5 tested tag SNPs of the PRKAA1 gene (rs13361707, rs154268, rs3805486, rs6882903, and rs10074991) were significantly associated with gastric cancer.An inhibitor of PRKAA1 promoted the secretion of IL6, whereas an agonist of PRKAA1 suppressed the production of IL6. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide corresponding to the residues around (Thr172) of Human Phospho-AMPKα |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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