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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LILRB2 Polyclonal Antibody

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货号 TMAB-08306

Anti-LILRB2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LILRB2。Anti-LILRB2 Polyclonal Antibody 可用于 WB。

Anti-LILRB2 Polyclonal Antibody

Anti-LILRB2 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08306

Anti-LILRB2 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LILRB2。Anti-LILRB2 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-LILRB2 Polyclonal Antibody is a Rabbit antibody targeting LILRB2. Anti-LILRB2 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Membrane.
组织特异性Expressed on monocytes and B-cells, and at lower levels on dendritic cells. Detected at low levels in natural killer (NK) cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Leukocyte immunoglobulin-like receptors (LIRs) are members of the immunoglobulin superfamily of glycoproteins and are predominantly expressed by monocytes, B cells, dendritic cells, natural killer (NK) cells, peripheral blood leukocytes and tissues such as placenta, lung and liver. These receptors all contain a cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM), have an inhibitory function and are type I membrane proteins. When they bind to MHC (or other ligands) and ITIM is tyrosine phosphorylated, protein-tyrosine phosphatases are recruited and an inhibitory signal cascade triggered. ILT-4, also designated LIR-2, MIR-10 or CD85D antigen, competes with CD8A for binding to class I MHC antigens.
抗原信息
免疫原
KLH conjugated synthetic peptide: human LILRB2
抗原种属
Human
基因名称
LILRB2
基因ID
10288
蛋白名称
Leukocyte immunoglobulin-like receptor subfamily B member 2
Uniprot ID
Q8N423
功能
Receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. Involved in the down-regulation of the immune response and the development of tolerance. Competes with CD8A for binding to class I MHC antigens. Inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
化学信息
分子量Theoretical: 65 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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