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Anti-HLA-DR Antibody-FITC (4D493)
还可以产品编号 TMAY-03604F
Anti-HLA-DR Antibody-FITC (4D493) 是一种 FITC-conjugated Mouse 抗体，靶向 HLA-DR。Anti-HLA-DR Antibody-FITC (4D493) 可用于 FCM。
Anti-HLA-DR Antibody-FITC (4D493)
Anti-HLA-DR Antibody-FITC (4D493)
还可以产品编号 TMAY-03604F
Anti-HLA-DR Antibody-FITC (4D493) 是一种 FITC-conjugated Mouse 抗体，靶向 HLA-DR。Anti-HLA-DR Antibody-FITC (4D493) 可用于 FCM。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-HLA-DR Antibody-FITC (4D493) is a FITC-conjugated Mouse antibody targeting HLA-DR. Anti-HLA-DR Antibody-FITC (4D493) can be used in FCM. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4D493 |
| 交叉反应 | Human |
| 验证活性 | Flow cytometric analysis of Human HLA-DR expression on human whole blood lymphocytes. Cells were stained with FITC-conjugated anti-Human HLA-DR. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable lymphocytes. |
| 应用 | FCM |
| 推荐剂量 | 1 μl/Test, 0.1 mg/ml |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | The monoclonal antibody was purified by affinity chromatography. Then it was conjugated with FITC under optimum conditions, and the unreacted FITC was removed. |
| 性状 | Liquid |
| 缓冲液 | PBS solution containing 0.5% BSA and 0.09% sodium azide |
| 研究背景 | HLA-DR is a major histocompatibility complex (MHC) class II antigen presentation molecule, critical for the activation of lymphocytes and the orchestration of adaptive immune responses. HLA-DR is normally expressed on antigen-presenting cells including monocytes, macrophages, dendritic cells and B cells, but expression can be induced on epithelial cells and tumour cells in response to inflammatory conditions. MHC class II antigen presentation molecules are responsible for presentation of exogenous antigens to CD4+helper T cells. HLA-DR expression in tumours has been positively associated with enhanced lymphocytic infiltration. HLA-DR has been used as a surrogate marker of immune competence in various clinical studies, and its loss in circulation has been linked with susceptibility to post-surgical infection and sepsis. |
| 偶联 | FITC |
| 其他可选修饰符 | PE |
| 可提供抗体种类 | 2 |
| 免疫原 | 0 |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. Sodium azide is toxic to cells and should be disposed of properly. Flush with large volumes of water during disposal. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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