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Anti-CD46 Antibody (1W587) 是一种 Rabbit 抗体,靶向 CD46。Anti-CD46 Antibody (1W587) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
Anti-CD46 Antibody (1W587) 是一种 Rabbit 抗体,靶向 CD46。Anti-CD46 Antibody (1W587) 可用于 WB,IHC-P,IHC-Fr,ICC/IF,IF。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,390 | 5日内发货 | |
| 100 μL | ¥ 2,485 | 5日内发货 |
| 产品描述 | Anti-CD46 Antibody (1W587) is a Rabbit antibody targeting CD46. Anti-CD46 Antibody (1W587) can be used in WB,IHC-P,IHC-Fr,ICC/IF,IF. |
| Ig Type | IgG |
| 克隆号 | 1W587 |
| 反应种属 | Human |
| 应用 | WBIHC-PIHC-FrICC/IFIF |
| 推荐剂量 | WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; ICC/IF: 1:50-200; IF: 1:100-500 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Isoform 1: Cytoplasmic vesicle, secretory vesicle, acrosome inner membrane; Single-pass type I membrane protein. Note=Inner acrosomal membrane of spermatozoa. Isoform 2: Secreted (Probable). |
| 组织特异性 | Present only in testis (at protein level). |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | CD46 is one of the membrane complement regulatory proteins. CD46 possesses C3b-binding and factor I cofactor activities which play important roles in the regulation of the complement activation pathway. CD46 is widely distributed on blood cells, endothelial cells, epithelial cells and tumor cell lines. CD46 exists as many isoforms in a variety of tissues. The antigen has a broad distribution and is present on leukocytes, platelets, endothelial cells, epithelial cells and fibroblasts. It is strongly expressed on salivary gland ducts and kidney ducts, moderately on lymphocytes and endothelium, and weakly on interstitial tissues and muscle cells, but not on erythrocytes. It is expressed on thymocytes, B cells, monocytes, granulocytes, NK cells, platelets, epithelial and endothelial cells. |
| 免疫原 | A synthesized peptide: human CD46 |
| 抗原种属 | Human |
| 基因名称 | CD46 |
| 基因ID | |
| 蛋白名称 | Membrane cofactor protein |
| Uniprot ID | |
| 功能 | May be involved in the fusion of the spermatozoa with the oocyte during fertilization. |
| 分子量 | Theoretical: 36 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |