购物车
全部删除
  • TargetMol
    您的购物车当前为空
前往下单页继续购物
顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CRBN Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-04637

Anti-CRBN Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CRBN。Anti-CRBN Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

Anti-CRBN Polyclonal Antibody 2

Anti-CRBN Polyclonal Antibody 2

一键复制产品信息
Rating icon 还可以
货号 TMAB-04637

Anti-CRBN Polyclonal Antibody 2 是一种 Rabbit 抗体，靶向 CRBN。Anti-CRBN Polyclonal Antibody 2 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,160
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,795
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
大包装 & 定制
加入购物车
TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。
实验操作小课堂
常见问题解答
查看更多
资源下载:
产品操作手册

产品介绍

生物活性
产品描述
Anti-CRBN Polyclonal Antibody 2 is a Rabbit antibody targeting CRBN. Anti-CRBN Polyclonal Antibody 2 can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Horse,Rabbit,Zebrafish,Sheep)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus. Membrane; Peripheral membrane protein
组织特异性Widely expressed. Highly expressed in brain.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景CRBN is a 442 amino acid protein which is highly concentrated in human brain tissue. CRBN functions are thought to be related to energy metabolism, learning and memory. Localized to the cytoplasm, CRBN acts as a protease in mitochondria and is thought to regulate the assembly of KCNT1, as well as the surface expression of KCNT1 in brain regions known to affect memory and learning, such as the hippocampus. The gene encoding CRBN belongs to a family of ATP-dependent lon proteases that play a role in membrane trafficking and proteolysis. Defects in the CRBN gene are associated with mild mental retardation.
抗原信息
免疫原
KLH conjugated synthetic peptide: human CRBN
抗原种属
Human
基因名称
CRBN
基因ID
51185
蛋白名称
Protein cereblon
Uniprot ID
Q96SW2
功能
Protein cereblon modulates cell surface expression of KCNT1 and may be involved in memory and learning. It is highly expressed in brain and defects in CRBN are the cause of non syndromic mental retardation autosomal recessive type 2A (MRT2A) [MIM:607417]. Although it contains a Lon domain also found in proteases of the peptidase S16 family, it does not contain the ATP binding and catalytic domains, suggesting that it has no protease activity.
化学信息
分子量Theoretical: 51 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

  • 稀释 计算器
Related Tags: buy Anti-CRBN Polyclonal Antibody 2 | purchase Anti-CRBN Polyclonal Antibody 2 | Anti-CRBN Polyclonal Antibody 2 cost | order Anti-CRBN Polyclonal Antibody 2 | Anti-CRBN Polyclonal Antibody 2 molecular weight