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TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P19438-1.

| 规格 | 价格 | 库存 | 数量 | 
|---|
| 生物活性 | Immobilized Human TNFR1, His Tag at 0.5 μg/ml (100 μl/Well). Dose response curve for Biotinylated Human TNF alpha, His Tag with the EC50 of 16.5 ng/ml determined by ELISA. | 
| 产品描述 | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) V2 is expressed in HEK293 Cells. The accession number is P19438-1. | 
| 种属 | Human | 
| 表达系统 | HEK293 Cells | 
| 标签 | C-His | 
| 蛋白编号 | P19438-1 | 
| 别名 | tumor necrosis factor receptor superfamily member 1A,TNF-R-I,TNFR60,TNF-R55,TNFR55,TNFR1-d2,TNFR1,TNF-R,TNFAR,TBP1,p60,p55-R,p55,MS5,FPF,CD120a | 
| 蛋白构建 | Leu30-Thr211 | 
| 蛋白纯度 | > 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC | 
| 分子量 | 23.3 kDa (Predicted); 38-48 kDa (Due to glycosylation) | 
| 内毒素 | < 1.0 EU/μg of the protein as determined by the LAL method. | 
| 蛋白性状 | Lyophilized powder | 
| 缓冲液 | Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. | 
| 存储 | Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. | 
| 运输方式 | In general, Lyophilized powders are shipping with blue ice. Solutions are shipping with dry ice. | 
| 研究背景 | Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2. In the setting of acute injury, selective inhibition of TNFR1 is predicted to attenuate the cell death and inflammation associated with TNF-α, while sparing or potentiating the protective effects of TNFR2 signalling. |