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Anti-Alpha-Synuclein Antibody (3Y979)

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货号 TMAB-02488

Anti-Alpha-Synuclein Antibody (3Y979) 是一种 Mouse 抗体，靶向 Alpha-Synuclein。Anti-Alpha-Synuclein Antibody (3Y979) 可用于 IHC-P,IHC-Fr,IF。

Anti-Alpha-Synuclein Antibody (3Y979)

Anti-Alpha-Synuclein Antibody (3Y979)

一键复制产品信息
Rating icon 还可以
货号 TMAB-02488

Anti-Alpha-Synuclein Antibody (3Y979) 是一种 Mouse 抗体，靶向 Alpha-Synuclein。Anti-Alpha-Synuclein Antibody (3Y979) 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

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产品描述
Anti-Alpha-Synuclein Antibody (3Y979) is a Mouse antibody targeting Alpha-Synuclein. Anti-Alpha-Synuclein Antibody (3Y979) can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
3Y979
反应种属
Human
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Cytoplasm. Membrane. Nucleus. Cell junction, synapse. Note=Membrane-bound in dopaminergic neurons.
组织特异性Expressed principally in brain but is also expressed in low concentrations in all tissues examined except in liver. Concentrated in presynaptic nerve terminals.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Alpha-Synuclein
抗原种属
Human
基因名称
SNCA
基因ID
6622
蛋白名称
alpha-synuclein
Uniprot ID
P37840
功能
May be involved in the regulation of dopamine release and transport. Induces fibrillization of microtubule-associated protein tau. Reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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