FABP3 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.8 kDa and the accession number is P11404.
生物活性 | Testing in progress |
产品描述 | FABP3 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.8 kDa and the accession number is P11404. |
种属 | Mouse |
表达系统 | E. coli |
标签 | Tag Free |
蛋白编号 | P11404 |
别名 | Fabph1, Fabph-1, Fabph4, fatty acid binding protein 3, Mdgi, Fabph-4, H-FABP |
蛋白构建 | Mouse Fabp3 (NP_034304.1) (Met1-Ala133) |
蛋白纯度 | > 95 % as determined by SDS-PAGE. |
分子量 | 14.8 kDa (predicted) |
内毒素 | Please contact us for more information. |
缓冲液 | Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS, pH 7.4. Typically, a mixture containing 5% to 8% trehalose, mannitol, and 0.01% Tween 80 is incorporated as a protective agent before lyophilization. |
复溶方法 | A Certificate of Analysis (CoA) containing reconstitution instructions is included with the products. Please refer to the CoA for detailed information. |
存储 |
It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at-80℃. For reconstituted protein solutions, the solution can be stored at -20°c to -80'c for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots. |
运输方式 |
In general, Lyophilized powders are shipping with blue ice. |
研究背景 | Fatty acid binding protein 3 (FABP3, also termed heart-type fatty acid binding protein) is a member of the intracellular lipid-binding protein family that may be essential in fatty acid transport, cell growth, cellular signaling and gene transcription. Previously FABP3 was involved in apoptosis-associated congenital cardiac malformations. FABP3 knockdown exhibited significant toxic effects on cardiac development and mitochondrial function, which may be responsible for the knockdown of FABP3-induced apoptosis. FABP3 as a candidate gene underlying the etiology of congenital heart defects. Overexpression of FABP3 inhibited cell growth and proliferation via negative regulation of the cell cycle and down-regulation of cell growth factors, but enhances cell survival in hypoxic or ischemic conditions. FABPs are known to be carrier proteins for transporting fatty acids and other lipophilic substances from the cytoplasm to the nucleus, where these lipids are released to a group of nuclear receptors such as peroxisome proliferator-activated receptors (PPARs). |
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FABP3 Protein, Mouse, Recombinant Fabph1 Fabph-1 Fabph4 fatty acid binding protein 3 Mdgi Fabph-4 H-FABP recombinant recombinant-proteins proteins protein