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Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) 是一种 Rabbit 抗体,靶向 Ferritin heavy chain 1/FTH1。Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) 可用于 WB,IHC,ICC。
Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) 是一种 Rabbit 抗体,靶向 Ferritin heavy chain 1/FTH1。Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) 可用于 WB,IHC,ICC。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,485 | 5日内发货 | |
100 μL | ¥ 2,495 | 5日内发货 |
产品描述 | Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) is a Rabbit antibody targeting Ferritin heavy chain 1/FTH1. Anti-Ferritin heavy chain 1/FTH1 Antibody (2J440) can be used in WB,IHC,ICC. |
别名 | FTHL6, FTH1, FTH, Ferritin heavy chain, Ferritin H subunit, Cell proliferation-inducing gene 15 protein |
Ig Type | IgG |
交叉反应 | Human,Mouse,Rat |
应用 | |
推荐剂量 | WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | Mammalian ferritins consist of 24 subunits made up of two types of poly-peptide chains, ferritin heavy chain and ferritin light chain, which each have unique functions. Ferritin heavy chains catalyze the first step in iron storage, the oxidation of FeII, whereas ferritin light chains promote the nucleation of ferrihydrite, enabling storage of FeIII. The most prominent role of mamma-lian ferritins is to provide iron-buffering capacity to cells. In addition to iron buffering, heavy chain ferritin is also involved in the regulation of thymidine biosynthesis via increased expression of cytoplasmic serine hydroxymethyltransferase, which is a limiting factor in thymidylate synthesis in MCF-7 cells. Light chain ferritin is involved in cataracts by at least two mechanisms: hereditary hyperferritinemia cataract syndrome, in which light chain ferritin is overexpressed; and oxidative stress, an important factor in the development of aging-related cataracts. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 21 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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