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CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi)

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货号 TMPK-00346

别名 TNFRSF8, D1S166EKi-1, CD30L receptor, CD30KI-1, CD30

The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).

CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi)

CD30/TNFRSF8 Protein, Human, Recombinant (His & Avi)

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SPR兼容缓冲液
货号 TMPK-00346 别名 TNFRSF8, D1S166EKi-1, CD30L receptor, CD30KI-1, CD30

The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).

规格价格库存数量
5 μg
¥ 246
6-8日内发货
10 μg
¥ 383
6-8日内发货
20 μg
¥ 616
5日内发货
50 μg
¥ 1,190
5日内发货
100 μg
¥ 1,990
5日内发货
200 μg
¥ 3,590
5日内发货
500 μg
¥ 8,000
5日内发货
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产品介绍


生物活性
产品描述
The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).
生物活性
Immobilized Human CD30, His Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Human CD30 Ligand, mFc (IgG2a) Tag with the EC50 of 10.5ng/ml determined by ELISA.
研究背景
The transmembrane receptor CD30 (TNFRSF8) and its ligand CD30L (CD153, TNFSF8) are members of the tumor necrosis factor (TNF) superfamily and display restricted expression in subpopulations of activated T-and B-cells in nonpathologic conditions. CD30 expression is upregulated in various hematological malignancies, including Reed-Sternberg cells in Hodgkin's disease (HD), anaplastic large cell lymphoma (ALCL) and subsets of Non-Hodgkin's lymphomas (NHLs).
种属
Human
表达系统
HEK293 Cells
标签C-His-Avi
蛋白编号P28908-1
蛋白构建Phe19-Lys379
蛋白纯度
> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状Lyophilized powder
缓冲液Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名TNFRSF8, D1S166EKi-1, CD30L receptor, CD30KI-1, CD30
内毒素< 1 EU/μg by the LAL method.
化学信息
分子量41.3 kDa (predicted). Due to glycosylation, the protein migrates to 68-95 kDa based on Tris-Bis PAGE result.
储存&溶解度
运输方式In general, Lyophilized powders are shipping with blue ice.
存储It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

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请阅读 重组蛋白用户指南 了解更多具体信息.
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