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顶部生物活性储存和溶解信息计算器

Anti-KRT5 Antibody (6Y466)

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产品编号 TMAY-00124

别名 KRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5

Anti-KRT5 Antibody (6Y466) 是一种 Rabbit 抗体，靶向 KRT5。Anti-KRT5 Antibody (6Y466) 可用于 IHC-P。

Anti-KRT5 Antibody (6Y466)

Anti-KRT5 Antibody (6Y466)

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产品编号 TMAY-00124 别名 KRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5

Anti-KRT5 Antibody (6Y466) 是一种 Rabbit 抗体，靶向 KRT5。Anti-KRT5 Antibody (6Y466) 可用于 IHC-P。

规格价格库存数量
100 μL
¥ 2,279
5日内发货
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产品介绍

生物活性
产品描述
Anti-KRT5 Antibody (6Y466) is a Rabbit antibody targeting KRT5. Anti-KRT5 Antibody (6Y466) can be used in IHC-P.
别名KRT5A, K5, EBS2F, EBS2E, EBS2D, EBS2C, EBS2B, EBS2A, EBS2, EBS1, DDD1, DDD, CK-5, CK5
Ig Type
Rabbit IgG
克隆号
6Y466
交叉反应
Human
特异性
Human
Mouse, Rat (Species predicted to react based on 100% sequence homology)
验证活性
1. Immunochemical staining of human CK5 in human skin with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
2. Immunochemical staining of human CK5 in human gastric cancer with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
3. Immunochemical staining of human CK5 in human breast carcinoma with rabbit monoclonal antibody (1:200, formalin-fixed paraffin embedded sections).
应用IHC-P
推荐剂量
IHC-P: 1:100-1:500
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with a synthetic peptide corresponding to the center region of the human KRT5.
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Keratin 5 is the major type II keratin of the basal cells of the epidermis and other stratified epithelia. With its type I partner, keratin 14, it constitutes a major fraction of the cytoskeleton of the basal cells. Epidermolysis bullosa simplex with mottled pigmentation (EBS-MP) is a rare dermatologic disorder of autosomal dominant inheritance with intraepidermal blistering after minor trauma, reticular hyperpigmentation unrelated to the blistering, nail dystrophy, and mild palmoplantar keratosis. Keratin 5 and keratin 14 are known to be essential for the basal keratinocyte cytoskeleton and are defective in several forms of epidermolysis bullosa simplex. Recently, a 71C-->T transition in the keratin 5 gene (KRT5) causing a P24L substitution was identified in some patients with EBS-MP.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
A synthetic peptide: center region of the human KRT5
抗原种属
Human
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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