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Anti-Caspase-7 Antibody (4K535)

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货号 TMAB-03670

Anti-Caspase-7 Antibody (4K535) 是一种 Rabbit 抗体,靶向 Caspase-7。Anti-Caspase-7 Antibody (4K535) 可用于 WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF。

Anti-Caspase-7 Antibody (4K535)

Anti-Caspase-7 Antibody (4K535)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03670

Anti-Caspase-7 Antibody (4K535) 是一种 Rabbit 抗体,靶向 Caspase-7。Anti-Caspase-7 Antibody (4K535) 可用于 WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF。

规格价格库存数量
25 μL
¥ 780
5日内发货
50 μL
¥ 1,380
5日内发货
100 μL
¥ 2,480
5日内发货
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产品介绍


生物活性
产品描述
Anti-Caspase-7 Antibody (4K535) is a Rabbit antibody targeting Caspase-7. Anti-Caspase-7 Antibody (4K535) can be used in WB,IHC-P,IHC-Fr,IF,FCM,ICC/IF.
Ig Type
IgG
克隆号
4K535
反应种属
Human
应用WBIHC-PIHC-FrIFFCMICC/IF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500; FCM: 1:50-100; ICC/IF: 1:50-200
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm.
组织特异性Highly expressed in lung, skeletal muscle, liver, kidney, spleen and heart, and moderately in testis. No expression in the brain.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of this caspase is cleaved by caspase3 and 10. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated synthetic peptide: human Caspase-7
抗原种属
Human
基因名称
CASP7
基因ID
蛋白名称
Caspase-7
Uniprot ID
功能
Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.
化学信息
分子量Theoretical: 20/33 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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