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Anti-Chymotrypsin C Antibody (2P796)
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产品编号 TMAY-01866
别名 ELA4, CLCR, chymotrypsin C (caldecrin)
Anti-Chymotrypsin C Antibody (2P796) 是一种 Rabbit 抗体，靶向 Chymotrypsin C。Anti-Chymotrypsin C Antibody (2P796) 可用于 ELISA。
Anti-Chymotrypsin C Antibody (2P796)
Anti-Chymotrypsin C Antibody (2P796)
还可以产品编号 TMAY-01866 别名 ELA4, CLCR, chymotrypsin C (caldecrin)
Anti-Chymotrypsin C Antibody (2P796) 是一种 Rabbit 抗体，靶向 Chymotrypsin C。Anti-Chymotrypsin C Antibody (2P796) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 100 μL | ¥ 2,279 | 5日内发货 |
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-Chymotrypsin C Antibody (2P796) is a Rabbit antibody targeting Chymotrypsin C. Anti-Chymotrypsin C Antibody (2P796) can be used in ELISA. |
| 别名 | ELA4, CLCR, chymotrypsin C (caldecrin) |
| Ig Type | Rabbit IgG |
| 克隆号 | 2P796 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:5000-1:10000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Rabbit |
| 构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CTRC / chymotrypsin C (rh CTRC / chymotrypsin C; TMPY-02480; Q99895; Met1-Leu268). |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | Chymotrypsin C (abbreviated for CTRC), also known as caldecrin or elastase4, is a digestive enzyme of the peptidase S1 family. This enzyme is synthesized as an inactivate chymotrypsinogen. On cleavage by trypsin into two parts that activate each other by removing two small peptides in a trans-proteolysis, chymotrypsin C produced. N-linked glycosylation of human CTRC is required for efficient folding and secretion, however, the N-linked glycan is unimportant for enzyme activity or inhibitor binding. It has been proposed that CTRC is a key regulator of digestive zymogen activation and a physiological co-activator of digestive carboxypeptidases proCPA1 and proCPA2. Mutations that abolish activity or secretion of CTRC increase the risk for chronic pancreatitis. It's speculated that CTRC might regulate pancreatic cancer cell migration in relation to cytokeratin 18 expression. The pancreatic cancer cell migration ability was downregulated in pancreatic cancer Aspc-1 cells that overexpressed CTRC, whereas the cell migration ability was upregulated in Aspc-1 cells in which CTRC was suppressed. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Protein: Human CTRC / chymotrypsin C protein (TMPY-02480) |
| 抗原种属 | Human |
| 研究领域 | Serine Proteases and Regulators |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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