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Anti-CD40 Ligand Antibody (6X569)

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产品编号 TMAY-00515

Anti-CD40 Ligand Antibody (6X569) 是一种 Rabbit 抗体,靶向 CD40 Ligand。Anti-CD40 Ligand Antibody (6X569) 可用于 ELISA。

Anti-CD40 Ligand Antibody (6X569)

Anti-CD40 Ligand Antibody (6X569)

Rating icon 还可以
产品编号 TMAY-00515

Anti-CD40 Ligand Antibody (6X569) 是一种 Rabbit 抗体,靶向 CD40 Ligand。Anti-CD40 Ligand Antibody (6X569) 可用于 ELISA。

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产品介绍

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产品描述
Anti-CD40 Ligand Antibody (6X569) is a Rabbit antibody targeting CD40 Ligand. Anti-CD40 Ligand Antibody (6X569) can be used in ELISA.
Ig Type
Monoclonal Rabbit IgG
克隆号
6X569
交叉反应
Human
应用
ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Human CD40 Ligand/CD40L/CD154 (rh CD40 Ligand/CD40L/CD154; TMPY-01758; NP_000065.1; Glu108-Leu261).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD154, also known as CD40 ligand or CD40L, is a member of the TNF superfamily. While CD154 was originally found on T cell surface, its expression has since been found on a wide variety of cells, including platelets, mast cells, macrophages and NK cells. CD154's ability is achieved through binding to the CD40 on antigen-presenting cells (APC). In the macrophage cells, the primary signal for activation is IFN-γ from Th1 type CD4 T cells. The secondary signal is CD40L on the T cell, which interacting with the CD40 molecules, helping increase the level of activation.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Human CD40 Ligand/CD40L/CD154 Protein (TMPY-01758)
抗原种属
Human
研究领域
Cancer Drug Targets
存储&运输
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

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