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Anti-CD40 Ligand Antibody (6X569) 是一种 Rabbit 抗体,靶向 CD40 Ligand。Anti-CD40 Ligand Antibody (6X569) 可用于 ELISA。
Anti-CD40 Ligand Antibody (6X569) 是一种 Rabbit 抗体,靶向 CD40 Ligand。Anti-CD40 Ligand Antibody (6X569) 可用于 ELISA。
产品描述 | Anti-CD40 Ligand Antibody (6X569) is a Rabbit antibody targeting CD40 Ligand. Anti-CD40 Ligand Antibody (6X569) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 6X569 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human CD40 Ligand/CD40L/CD154 (rh CD40 Ligand/CD40L/CD154; TMPY-01758; NP_000065.1; Glu108-Leu261). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD154, also known as CD40 ligand or CD40L, is a member of the TNF superfamily. While CD154 was originally found on T cell surface, its expression has since been found on a wide variety of cells, including platelets, mast cells, macrophages and NK cells. CD154's ability is achieved through binding to the CD40 on antigen-presenting cells (APC). In the macrophage cells, the primary signal for activation is IFN-γ from Th1 type CD4 T cells. The secondary signal is CD40L on the T cell, which interacting with the CD40 molecules, helping increase the level of activation.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
偶联 | Unconjugated |
免疫原 | Recombinant Human CD40 Ligand/CD40L/CD154 Protein (TMPY-01758) |
抗原种属 | Human |
研究领域 | Cancer Drug Targets |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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