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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-COPS8 Antibody (9F343)

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货号 TMAB-04577

Anti-COPS8 Antibody (9F343) 是一种 Rabbit 抗体，靶向 COPS8。Anti-COPS8 Antibody (9F343) 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-COPS8 Antibody (9F343)

Anti-COPS8 Antibody (9F343)

一键复制产品信息
Rating icon 还可以
货号 TMAB-04577

Anti-COPS8 Antibody (9F343) 是一种 Rabbit 抗体，靶向 COPS8。Anti-COPS8 Antibody (9F343) 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
25 μL
¥ 795
5日内发货
50 μL
¥ 1,390
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-COPS8 Antibody (9F343) is a Rabbit antibody targeting COPS8. Anti-COPS8 Antibody (9F343) can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
克隆号
9F343
反应种属
Human,Mouse,Rat
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Monoclonal
宿主来源Rabbit
亚细胞定位Cytoplasm. Nucleus.
构建方式Recombinant Antibody
纯化方式Protein A purified
性状Liquid
缓冲液10mM phosphate buffered saline (pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
研究背景Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2.
抗原信息
免疫原
A synthesized peptide: human COPS8
抗原种属
Human
基因名称
COPS8
基因ID
10920
蛋白名称
COP9 signalosome complex subunit 8
Uniprot ID
Q99627
功能
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.
化学信息
分子量Theoretical: 23 kDa. Actual: 20 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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