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Anti-IL-23R Polyclonal Antibody

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货号 TMAB-07642

Anti-IL-23R Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL-23R。Anti-IL-23R Polyclonal Antibody 可用于 WB,ELISA。

Anti-IL-23R Polyclonal Antibody

Anti-IL-23R Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-07642

Anti-IL-23R Polyclonal Antibody 是一种 Rabbit 抗体,靶向 IL-23R。Anti-IL-23R Polyclonal Antibody 可用于 WB,ELISA。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍


生物活性
产品描述
Anti-IL-23R Polyclonal Antibody is a Rabbit antibody targeting IL-23R. Anti-IL-23R Polyclonal Antibody can be used in WB,ELISA.
Ig Type
IgG
反应种属
Human,Mouse,Rat
应用WBELISA
推荐剂量
WB: 1:500-1000; ELISA: 1:5000-10000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Single-pass type I membrane protein.
组织特异性Expressed by monocytes, Th1, Th0, NK and dendritic cells. Isoform 1 is specifically expressed in NK cells.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a subunit of the receptor for IL23A/IL23. This protein pairs with the receptor molecule IL12RB1/IL12Rbeta1, and both are required for IL23A signaling. This protein associates constitutively with Janus kinase 2 (JAK2), and also binds to transcription activator STAT3 in a ligand-dependent manner.
抗原信息
免疫原
KLH conjugated synthetic peptide: human IL-23R
抗原种属
Human
基因名称
IL23R
基因ID
蛋白名称
Interleukin-23 receptor
Uniprot ID
功能
Associates with IL12RB1 to form the interleukin-23 receptor. Binds IL23 and mediates T-cells, NK cells and possibly certain macrophage/myeloid cells stimulation probably through activation of the Jak-Stat signaling cascade. IL23 functions in innate and adaptive immunity and may participate in acute response to infection in peripheral tissues. IL23 may be responsible for autoimmune inflammatory diseases and be important for tumorigenesis.
化学信息
分子量Theoretical: 67 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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