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顶部生物活性储存和溶解信息计算器

Anti-TPM1 Antibody (5W651)

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Anti-TPM1 Antibody (5W651)
产品编号 TMAC-04136
别名 Tropomyosin-1, Tropomyosin alpha-1 chain, TPMA, TPM1, Alpha-tropomyosin

Anti-TPM1 Antibody (5W651) 是一种 Rabbit 抗体，靶向 TPM1。Anti-TPM1 Antibody (5W651) 可用于 WB,IHC,FCM。

Anti-TPM1 Antibody (5W651)

Anti-TPM1 Antibody (5W651)

Rating icon 还可以
Anti-TPM1 Antibody (5W651)
产品编号 TMAC-04136 别名 Tropomyosin-1, Tropomyosin alpha-1 chain, TPMA, TPM1, Alpha-tropomyosin

Anti-TPM1 Antibody (5W651) 是一种 Rabbit 抗体，靶向 TPM1。Anti-TPM1 Antibody (5W651) 可用于 WB,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,490
5日内发货
100 μL
¥ 2,495
5日内发货
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产品介绍

生物活性
产品描述
Anti-TPM1 Antibody (5W651) is a Rabbit antibody targeting TPM1. Anti-TPM1 Antibody (5W651) can be used in WB,IHC,FCM.
别名Tropomyosin-1, Tropomyosin alpha-1 chain, TPMA, TPM1, Alpha-tropomyosin
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of Tropomyosin 1 on rat heart tissue using anti-Tropomyosin 1 antibody at 1/1,000 dilution.
2. Immunohistochemical analysis of paraffin-embedded rat smooth muscle tissue using anti-Tropomyosin 1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human heart tissue using anti-Tropomyosin 1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse skeletal muscle tissue using anti-Tropomyosin 1 antibody. Counter stained with hematoxylin.
5. Flow cytometric analysis of MCF-7 cells with Tropomyosin 1 antibody at 1/100 dilution (purple) compared with an unlabelled control (cells without incubation with primary antibody; yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
应用
WB
IHC
FCM
推荐剂量
WB: 1:500-2000; IHC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Tropomyosins are a group of structural proteins. Tropomyosins are present in virtually all eukaryotic cells, both muscle and non-muscle, where they bind Actin filaments and function to modulate Actin-Myosin interaction and stabilize Actin filament structure. Tropomyosin α is encoded by the TPM1 gene, which maps to human chromosome 15q22.1 and undergoes alternative splicing to generate at least four isoforms, including skeletal muscle (isoform 1), smooth muscle (isoform 2), fibroblast/TM3 (isoform 3) and isoform 4. Tropomyosin β is encoded by the TPM2 gene, which maps to human chromosome 9p13.3 and undergoes alternative splicing to generate three isoforms, including skeletal muscle (isoform 1), non-muscle/fibroblast TM36/epithelial TMe1 (isoform 2) and non-muscle (isoform 3). Troponin I binds Tropomyosin at a specific region and the association of Tropomyosin-Troponin with Actin filaments may increase the rigidity of Actin filaments. Tropomyosin also interacts with Caldesmon to regulate smooth muscle contraction.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: human Tropomyosin 1 aa 100-300
抗原种属
human
Uniprot ID
P09493
化学信息
分子量Theoretical: 33 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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关键词

α-tropomyosinαtropomyosinTropomyosin1Tropomyosin α-1 chainTropomyosin a-1 chainTPM 1a-tropomyosin

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