规格

价格

库存

数量

10 mg

¥ 129

现货

25 mg

¥ 245

现货

50 mg

¥ 448

现货

100 mg

¥ 795

现货

500 mg

¥ 1,970

现货

1 mL x 10 mM (in DMSO)

¥ 143

现货

生物活性

产品描述	Levamlodipine besylate ((S)-Amlodipine Besylate (103129-82-4(free base))) , also known as S-amlodipine, is a pharmacologically active enantiomer of amlodipine, an antihypertensive and anti-anginal medication. Levamlodipine besylate belongs to the dihydropyridine group of calcium channel blockers. The names S-amlodipine and levamlodipine may be used interchangeably as both substances are the same, however, with differing nomenclature. As a racemic mixture, amlodipine contains (R) and (S)-amlodipine isomers, but only (S)-amlodipine as the active moiety possesses therapeutic activity.
靶点活性	Ca2+ channel:
体外活性	Amlodipine是一种钙通道阻滞剂，用于治疗心绞痛和高血压。作为一种外消旋混合物，amlodipine包含(R)-amlodipine和(S)-amlodipine异构体，但只有具有治疗活性的(S)-amlodipine是活性成分。
别名	左旋氨氯地平, 苯磺酸左氨氯地平, (S)-Amlodipine Besylate (103129-82-4(free base))

化学信息

分子量	567.05
分子式	C₂₆H₃₁ClN₂O₈S
CAS No.	150566-71-5
Smiles	OS(=O)(=O)c1ccccc1.CCOC(=O)C1=C(COCCN)NC(C)=C([C@@H]1c1ccccc1Cl)C(=O)OC
密度	1.228 g/cm3

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

DMSO: 60 mg/mL (105.81 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (3.53 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.7635 mL	8.8176 mL	17.6351 mL	88.1756 mL
5 mM	0.3527 mL	1.7635 mL	3.5270 mL	17.6351 mL
10 mM	0.1764 mL	0.8818 mL	1.7635 mL	8.8176 mL
20 mM	0.0882 mL	0.4409 mL	0.8818 mL	4.4088 mL
50 mM	0.0353 mL	0.1764 mL	0.3527 mL	1.7635 mL
100 mM	0.0176 mL	0.0882 mL	0.1764 mL	0.8818 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

Levamlodipine besylate

Levamlodipine besylate

产品介绍

引用文献

计算器

体内实验配液计算器

剂量转换

关键词

Levamlodipine besylate

Levamlodipine besylate