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Anti-SDF-1/CXCL12 Antibody (6G646) 是一种 Rabbit 抗体,靶向 SDF-1/CXCL12。Anti-SDF-1/CXCL12 Antibody (6G646) 可用于 WB,ICC/IF。
Anti-SDF-1/CXCL12 Antibody (6G646) 是一种 Rabbit 抗体,靶向 SDF-1/CXCL12。Anti-SDF-1/CXCL12 Antibody (6G646) 可用于 WB,ICC/IF。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 μL | ¥ 1,480 | 5日内发货 | |
100 μL | ¥ 2,485 | 5日内发货 |
产品描述 | Anti-SDF-1/CXCL12 Antibody (6G646) is a Rabbit antibody targeting SDF-1/CXCL12. Anti-SDF-1/CXCL12 Antibody (6G646) can be used in WB,ICC/IF. |
别名 | TPAR1, TLSF, SDF-1, SDF1, SCYB12, PBSF, IRH, chemokine (C-X-C motif) ligand 12 |
Ig Type | IgG |
交叉反应 | Human |
验证活性 | 1. ICC staining SDF1 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 2. ICC staining SDF1 in SW480 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining SDF1 in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
应用 | |
推荐剂量 | WB: 1:1000-2000; ICC/IF: 1:50-200 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | Recombinant Antibody |
纯化方式 | ProA affinity purified |
性状 | Liquid |
缓冲液 | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
研究背景 | The stromal cell derived factor 1 (SDF1, CXCL12) is a small, pro-inflammatory chemoattractant cytokine that regulates leukocyte trafficking through interactions with its cognate 7-transmembrane G protein-coupled receptors. The SDF1 receptor, CXCR4, also serves as a coreceptor for the entry of human immunodeficiency virus into target cells. SDF1 may regulate homing and maintenance of CXCR4-expressing stem or progenitor cells, including embryonic and many somatic stem cells. Many cancer cells express CXCR4, suggesting that SDF1 plays a role in cancer metastasis. Alternative splicing and differential processing during maturation produce a pair of SDF1 isoforms (SDF1α and SDF1β) that have different properties and biological activities. Additional isoforms of SDF1 have been reported. |
偶联 | Unconjugated |
免疫原 | Recombinant Protein |
Uniprot ID |
分子量 | Theoretical: 11 kDa. |
储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
运输方式 | Shipping with blue ice. |
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