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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-CAMKK2 Antibody (7J726)

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货号 TMAB-03598

Anti-CAMKK2 Antibody (7J726) 是一种 Mouse 抗体，靶向 CAMKK2。Anti-CAMKK2 Antibody (7J726) 可用于 WB。

Anti-CAMKK2 Antibody (7J726)

Anti-CAMKK2 Antibody (7J726)

一键复制产品信息
Rating icon 还可以
货号 TMAB-03598

Anti-CAMKK2 Antibody (7J726) 是一种 Mouse 抗体，靶向 CAMKK2。Anti-CAMKK2 Antibody (7J726) 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,975
5日内发货
库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单
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产品介绍

生物活性
产品描述
Anti-CAMKK2 Antibody (7J726) is a Mouse antibody targeting CAMKK2. Anti-CAMKK2 Antibody (7J726) can be used in WB.
Ig Type
IgG1, k
克隆号
7J726
反应种属
Human,Mouse
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Monoclonal
宿主来源Mouse
亚细胞定位Nucleus. Cytoplasm. Cell projection. Note=Predominantly nuclear in unstimulated cells. Found in the cytoplasm and neurites after forskolin induction.
组织特异性Ubiquitously expressed with higher levels in the brain. Intermediate levels are detected in spleen, prostate, thyroid and leukocytes. The lowest level is in lung.
构建方式Hybridoma Monoclonal Antibody
纯化方式Protein G purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq, Jul 2008].
抗原信息
免疫原
Recombinant Protein: human CAMKK2
抗原种属
Human
基因名称
CAMKK2
基因ID
10645
蛋白名称
Calcium/calmodulin-dependent protein kinase kinase 2
Uniprot ID
Q96RR4
功能
Calcium/calmodulin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellular processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodulin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase (AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimulated in response to Ca(2+) signals. Seems to be involved in hippocampal activation of CREB1. May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
化学信息
分子量Theoretical: 55 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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