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别名 IFRC, IFN-α-REC, IFN-α/β R1, IFN-R-1, IFNbR1, IFNBR, IFN-aR1, IFNAR1, IFNAR, IFN-alpha-REC, IFN-alpha/β R1, IFN-alpha/beta R1, IFN α/β R1, CRF2-1, AVP
Anti-IFNAR1 Antibody (5I705) 是一种抗体,靶向 IFNAR1。Anti-IFNAR1 Antibody (5I705) 可用于 ELISA。
Anti-IFNAR1 Antibody (5I705) 是一种抗体,靶向 IFNAR1。Anti-IFNAR1 Antibody (5I705) 可用于 ELISA。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,315 | 5日内发货 | |
| 100 μL | ¥ 2,185 | 5日内发货 |
| 产品描述 | Anti-IFNAR1 Antibody (5I705) is an antibody targeting IFNAR1. Anti-IFNAR1 Antibody (5I705) can be used in ELISA. |
| 别名 | IFRC, IFN-α-REC, IFN-α/β R1, IFN-R-1, IFNbR1, IFNBR, IFN-aR1, IFNAR1, IFNAR, IFN-alpha-REC, IFN-alpha/β R1, IFN-alpha/beta R1, IFN α/β R1, CRF2-1, AVP |
| Ig Type | Rabbit IgG |
| 克隆号 | 5I705 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 抗体种类 | Monoclonal |
| 亚细胞定位 | [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Late endosome. Lysosome. |
| 组织特异性 | IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resi |
| 构建方式 | Recombinant Antibody |
| 纯化方式 | Affinity-chromatography |
| 性状 | Liquid |
| 缓冲液 | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| 研究背景 | Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway. |
| 偶联 | Unconjugated |
| 免疫原 | A synthetic peptide: Human IFNAR1 |
| 抗原种属 | Human |
| 基因名称 | IFNAR1 |
| 基因ID | |
| Uniprot ID | |
| 研究领域 | Immunology |
| 储存方式 | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
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