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Anti-MOG Antibody (3Q341) 是一种 Rabbit 抗体,靶向 MOG。Anti-MOG Antibody (3Q341) 可用于 ELISA。
Anti-MOG Antibody (3Q341) 是一种 Rabbit 抗体,靶向 MOG。Anti-MOG Antibody (3Q341) 可用于 ELISA。
产品描述 | Anti-MOG Antibody (3Q341) is a Rabbit antibody targeting MOG. Anti-MOG Antibody (3Q341) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 3Q341 |
交叉反应 | Human |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Human MOG (rh MOG; TMPY-00994; NP_996532.2; Gly 30-Tyr 149). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | Myelin oligodendrocyte glycoprotein (MOG) is a transmembrane protein belonging to the immunoglobulin superfamily and contains an Ig-like domain followed by two potential membrane-spanning regions. MOG is expressed only in the CNS with very low content (approximately 0.1% total proteins) in the oligodendrogliocyte membrane. Three possible functions for MOG were suggested: (a) a cellular adhesive molecule, (b) a regulator of oligodendrocyte microtubule stability, and (c) a mediator of interactions between myelin and the immune system, in particular, the complement cascade. A direct interaction might exist between the membrane-associated regions of MOG and the myelin-specific glycolipid galactocerebroside (Gal-C), and such an interaction may have important consequences regarding the membrane topology and function of both molecules. It is considered that MOG is an autoantigen capable to produce demyelinating multiple sclerosis-like diseases in experimental animals. |
偶联 | Unconjugated |
免疫原 | Recombinant Human MOG Protein (TMPY-00994) |
抗原种属 | Human |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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