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Anti-4-1BB Ligand/TNFSF9 Antibody-PE (8F465) 是一种 PE-conjugated Rabbit 抗体,靶向 4-1BB Ligand/TNFSF9。Anti-4-1BB Ligand/TNFSF9 Antibody-PE (8F465) 可用于 FCM。
Anti-4-1BB Ligand/TNFSF9 Antibody-PE (8F465) 是一种 PE-conjugated Rabbit 抗体,靶向 4-1BB Ligand/TNFSF9。Anti-4-1BB Ligand/TNFSF9 Antibody-PE (8F465) 可用于 FCM。
产品描述 | Anti-4-1BB Ligand/TNFSF9 Antibody-PE (8F465) is a PE-conjugated Rabbit antibody targeting 4-1BB Ligand/TNFSF9. Anti-4-1BB Ligand/TNFSF9 Antibody-PE (8F465) can be used in FCM. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8F465 |
交叉反应 | Mouse |
验证活性 | Flow cytometric analysis of Mouse 4-1BBL(TNFSF9) expression on RAW264.7 cells. Cells were stained with PE-conjugated anti-Mouse 4-1BBL(TNFSF9). The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells. |
应用 | FCM |
推荐剂量 | 10 μl/Test, 0.1 mg/ml |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse 4-1BBL / CD137L / TNFSF9 (rM 4-1BBL / CD137L / TNFSF9; TMPY-00959; NP_033430.1; Arg 104-Glu 309) and conjugated with PE under optimum conditions, the unreacted PE was removed. |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | PBS solution containing 0.5% BSA and 0.03%ProClin300 |
研究背景 | 4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: FCM AntibodiesImmune Checkpoint Detection: ICC AntibodiesImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
偶联 | PE |
其他可选修饰符 | Unconjugated/APC/PerCP/FITC |
可提供抗体种类 | 5 |
免疫原 | Recombinant Mouse 4-1BBL / CD137L / TNFSF9 protein (TMPY-00959) |
抗原种属 | Mouse |
研究领域 | Cancer Drug Targets |
储存方式 | Store at 2°C-8°C for 12 months, do not freeze. Keep away from direct sunlight. |
运输方式 | Shipping with blue ice. |
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