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Anti-CD93/C1qR1 Antibody (8K152) 是一种 Rabbit 抗体,靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody (8K152) 可用于 ELISA。
Anti-CD93/C1qR1 Antibody (8K152) 是一种 Rabbit 抗体,靶向 CD93/C1qR1。Anti-CD93/C1qR1 Antibody (8K152) 可用于 ELISA。
产品描述 | Anti-CD93/C1qR1 Antibody (8K152) is a Rabbit antibody targeting CD93/C1qR1. Anti-CD93/C1qR1 Antibody (8K152) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
克隆号 | 8K152 |
交叉反应 | Rat |
应用 | ELISA |
推荐剂量 | ELISA: 1:5000-1:10000 |
抗体种类 | Monoclonal |
宿主来源 | Rabbit |
构建方式 | This antibody was obtained from a rabbit immunized with purified, recombinant Rat CD93 / C1qR (rR CD93 / C1qR; TMPY-00306; Q9ET61; Met1-Lys571). |
纯化方式 | Protein A |
性状 | Liquid |
缓冲液 | 0.2 μm filtered solution in PBS |
研究背景 | CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protein expressed on monocytes, neutrophils, endothelial cells, and stem cells. CD93 was originally identified as a myeloid cell-surface marker and subsequently associated with an ability to modulate phagocytosis of suboptimally opsonized immunoglobulin G and complement particles in vitro. CD93/C1qR, a receptor expressed during early B-cell development, is reinduced during plasma-cell differentiation. High CD93/CD138 expression was restricted to antibody-secreting cells both in T-dependent and T-independent responses as naive, memory, and germinal-center B cells remained CD93-negative. CD93 was expressed on (pre)plasmablasts/plasma cells, including long-lived plasma cells that showed decreased cell cycle activity, high levels of isotype-switched Ig secretion, and modification of the transcriptional network. CD93 is important for the maintenance of plasma cells in bone marrow niches. |
偶联 | Unconjugated |
免疫原 | Recombinant Rat CD93 / C1qR Protein (TMPY-00306) |
抗原种属 | Rat |
储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
运输方式 | Shipping with blue ice. |
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