Anti-HIV agent 1 (compound 10i) is a potent antiviral agent with significant activity against HIV, showing an IC50 of 10.6 nM. It exhibits moderate or negligible inhibitory activity against RT mutant strains, while maintaining efficacy against the wild-type virus. Additionally, anti-HIV agent 1 demonstrates pronounced dual inhibitory effects on both the viral attachment and reverse transcription stages of the virus life cycle. This compound is applicable for research in HIV infection.

HIV-1:10.6 nM