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Anti-DEC-205 Antibody (4V35)
还可以产品编号 TMAY-02827
Anti-DEC-205 Antibody (4V35) 是一种 Mouse 抗体，靶向 DEC-205。Anti-DEC-205 Antibody (4V35) 可用于 ELISA。
Anti-DEC-205 Antibody (4V35)
Anti-DEC-205 Antibody (4V35)
还可以产品编号 TMAY-02827
Anti-DEC-205 Antibody (4V35) 是一种 Mouse 抗体，靶向 DEC-205。Anti-DEC-205 Antibody (4V35) 可用于 ELISA。
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产品介绍
生物活性
偶联与修饰
抗原信息
| 产品描述 | Anti-DEC-205 Antibody (4V35) is a Mouse antibody targeting DEC-205. Anti-DEC-205 Antibody (4V35) can be used in ELISA. |
| Ig Type | Monoclonal Mouse IgG1 |
| 克隆号 | 4V35 |
| 交叉反应 | Human |
| 应用 | ELISA |
| 推荐剂量 | ELISA: 1:1000-1:2000 |
| 抗体种类 | Monoclonal |
| 宿主来源 | Mouse |
| 构建方式 | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LY75 / DEC-205 / CD205 (rh LY75 / DEC-205 / CD205; TMPY-00322; NP_002340.2;Ala32-Gly1664). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| 纯化方式 | Protein A |
| 性状 | Liquid |
| 缓冲液 | 0.2 μm filtered solution in PBS |
| 研究背景 | LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways implicated in cell proliferation and metabolism, while pathways associated with cell signaling and adhesion, complement activation, and immune response were mostly suppressed. Moreover, LY75 suppression had an opposite effect on EOC cell lines with the epithelial phenotype (A2780s and OV2008), by directing epithelial-to-mesenchymal transition (EMT) associated with reduced capacity for in vivo EOC cell colonization, as similar/identical signaling pathways were reversely regulated, when compared to mesenchymal LY75 knockdown EOC cells. Diseases associated with LY75 include Pneumonic Plague and Adenoiditis. |
| 偶联 | Unconjugated |
| 免疫原 | Recombinant Human LY75 / DEC-205 / CD205 Protein (TMPY-00322) |
| 抗原种属 | Human |
存储&运输
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| 运输方式 | Shipping with blue ice. |
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计算器
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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