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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-NR2E1 Polyclonal Antibody

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货号 TMAB-09616

Anti-NR2E1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NR2E1。Anti-NR2E1 Polyclonal Antibody 可用于 WB。

Anti-NR2E1 Polyclonal Antibody

Anti-NR2E1 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-09616

Anti-NR2E1 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 NR2E1。Anti-NR2E1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,785
5日内发货
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产品介绍

生物活性
产品描述
Anti-NR2E1 Polyclonal Antibody is a Rabbit antibody targeting NR2E1. Anti-NR2E1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Dog,Pig,Cow,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus.
组织特异性Brain specific. Present in all brain sections tested, highest levels in the caudate nucleus and hippocampus, weakest levels in the thalamus.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景NR2 proteins are a large family of nuclear hormone receptor transcription factors. The proteins belonging to this family are characterized by discrete domains functioning in DNA and ligand binding. NR2E1 (nuclear receptor subfamily 2, group E, member 1), also known as TLX, is an essential component in the formation of synaptic plasticity and dendritic structure in retinal astrocytes. In addition, NR2E1 is a orphan receptor that binds DNA as part of the hormone response element (HRE), a transcription regulator for hormones. DNA-binding orphan receptors have the conserved sequence 5'-AAGGTCA-3', a motif that determines substrate binding specificity. NR2E1 is expressed in brain tissue, with highest levels in astrocytes, and is localized to the nucleus. Mutations in the gene that encodes NR2E1 may lead to retinal dystrophy, a disorder characterized by a reduction in the thickness of the retina.
抗原信息
免疫原
KLH conjugated synthetic peptide: human NR2E1
抗原种属
Human
基因名称
NR2E1
基因ID
7101
蛋白名称
Nuclear receptor subfamily 2 group E member 1
Uniprot ID
Q9Y466
功能
Orphan receptor that binds DNA as a monomer to hormone response elements (HRE) containing an extended core motif half-site sequence 5'-AAGGTCA-3' in which the 5' flanking nucleotides participate in determining receptor specificity. May be required for brain development. May be involved in the regulation of retinal development.
化学信息
分子量Theoretical: 43 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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