Name: B7-H3 Protein, Human, Recombinant (aa 29-245, His)
Brand: TargetMol
SKU: TMPK-01018
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 283

6-8日内发货

10 μg

¥ 446

6-8日内发货

20 μg

¥ 723

5日内发货

50 μg

¥ 1,380

5日内发货

100 μg

¥ 2,360

5日内发货

200 μg

¥ 4,280

5日内发货

500 μg

¥ 9,490

5日内发货

生物活性

产品描述	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 24.7 kDa and the accession number is Q5ZPR3-2.
生物活性	Immobilized Human B7-H3, His Tag at 0.5μg/ml (100μl/Well) on the plate. Dose response curve for Anti-B7-H3 Antibody, hFc Tag with the EC50 of 29.4ng/ml determined by ELISA.
研究背景	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction.
种属	Human
表达系统	HEK293 Cells
标签	C-His
蛋白编号	Q5ZPR3-2
蛋白构建	Leu29-Pro245
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	PSEC0249, PRO352, CD276, B7-H3, B7H3, B7 homolog 3, UNQ309
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	24.7 kDa (predicted). Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

B7-H3 Protein, Human, Recombinant (aa 29-245, His)

B7-H3 Protein, Human, Recombinant (aa 29-245, His)

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