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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-Phospho-MEK3 (Thr222) Polyclonal Antibody

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货号 TMAB-10987

Anti-Phospho-MEK3 (Thr222) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MEK3 (Thr222)。Anti-Phospho-MEK3 (Thr222) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-Phospho-MEK3 (Thr222) Polyclonal Antibody

Anti-Phospho-MEK3 (Thr222) Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-10987

Anti-Phospho-MEK3 (Thr222) Polyclonal Antibody 是一种 Rabbit 抗体，靶向 Phospho-MEK3 (Thr222)。Anti-Phospho-MEK3 (Thr222) Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,165
5日内发货
100 μL
¥ 1,960
5日内发货
200 μL
¥ 2,795
5日内发货
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产品介绍

生物活性
产品描述
Anti-Phospho-MEK3 (Thr222) Polyclonal Antibody is a Rabbit antibody targeting Phospho-MEK3 (Thr222). Anti-Phospho-MEK3 (Thr222) Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Chicken,Cow,Horse,Sheep)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cytoplasm; cytoskeleton.
组织特异性Abundant expression is seen in the skeletal muscle. It is also widely expressed in other tissues.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter. Expression of RAS oncogene is found to result in the accumulation of the active form of this kinase, which thus leads to the constitutive activation of MAPK14, and confers oncogenic transformation of primary cells. The inhibition of this kinase is involved in the pathogenesis of Yersina pseudotuberculosis. Multiple alternatively spliced transcript variants that encode distinct isoforms have been reported for this gene. [provided by RefSeq].
抗原信息
免疫原
KLH conjugated Synthesised phosphopeptide: human MEK3 around the phosphorylation site of Thr222
抗原种属
Human
基因名称
MAP2K3
基因ID
5606
蛋白名称
Dual specificity mitogen-activated protein kinase kinase 3
Uniprot ID
P46734
功能
Dual specificity kinase. Is activated by cytokines and environmental stress in vivo. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in the MAP kinase p38.
化学信息
分子量Theoretical: 39 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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