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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-LYK5 Polyclonal Antibody

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货号 TMAB-08467

Anti-LYK5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LYK5。Anti-LYK5 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

Anti-LYK5 Polyclonal Antibody

Anti-LYK5 Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-08467

Anti-LYK5 Polyclonal Antibody 是一种 Rabbit 抗体，靶向 LYK5。Anti-LYK5 Polyclonal Antibody 可用于 WB,IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,970
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍

生物活性
产品描述
Anti-LYK5 Polyclonal Antibody is a Rabbit antibody targeting LYK5. Anti-LYK5 Polyclonal Antibody can be used in WB,IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rat,Dog,Pig,Cow,Horse,Rabbit)
应用WBIHC-PIHC-FrIF
推荐剂量
WB: 1:500-2000; IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Nucleus. Cytoplasm.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Members of the STE-20 like kinase family are known to stimulate MAPK pathways by directly activating MAPKKK. LYK5 is a novel pseudokinase member of this family consisting of a STE-20 like kinase domain but lacks several residues that are required for its catalytic activity. It specifically binds LKB1 and plays a key role in regulating the tumor suppressor activities of LKB1. It functions as an upstream activator of LKB1 and also directs the sub-cellular localization of LKB1 by anchoring it in the cytoplasm. LYK5-LKB1 interaction results in phosphorylation of LYK5 and enhanced autophosphorylation of LKB1.
抗原信息
免疫原
KLH conjugated synthetic peptide: human LYK5
抗原种属
Human
基因名称
STRADA
基因ID
92335
蛋白名称
STE20-related kinase adapter protein alpha
Uniprot ID
Q7RTN6
功能
Pseudokinase which, in complex with CAB39/MO25 (CAB39/MO25alpha or CAB39L/MO25beta), binds to and activates STK11/LKB1. Adopts a closed conformation typical of active protein kinases and binds STK11/LKB1 as a pseudosubstrate, promoting conformational change of STK11/LKB1 in an active conformation.
化学信息
分子量Theoretical: 48 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

计算器

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