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Anti-Cellular Apoptosis Susceptibility Antibody (8O505)

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Anti-Cellular Apoptosis Susceptibility Antibody (8O505)
产品编号 TMAC-00813
别名 XPO2_HUMAN, XPO2, XPO 2, MGC130037, MGC130036, MGC117283, Importin-alpha re-exporter, Importin alpha re exporter, Exportin-2, Exportin2, Exportin 2, Exp2, Exp 2, CSE1L, CSE1 chromosome segregation 1 like protein, CSE1 chromosome segregation 1 like (yeast), CSE1 chromosome segregation 1 like, CSE1, CSE 1L, CSE 1 chromosome segregation 1 like protein, CSE 1 chromosome segregation 1 like, CSE 1, Chromosome segregation gene CSE1, Chromosome segregation 1-like protein, Chromosome segregation 1 like protein, Chromosome segregation 1 Like, Chromosome segregation 1 (yeast homolog) like, Cellular apoptosis susceptibility protein, CAS

Anti-Cellular Apoptosis Susceptibility Antibody (8O505) 是一种 Rabbit 抗体，靶向 Cellular Apoptosis Susceptibility。Anti-Cellular Apoptosis Susceptibility Antibody (8O505) 可用于 WB,ICC,IF,IHC,FCM。

Anti-Cellular Apoptosis Susceptibility Antibody (8O505)

Anti-Cellular Apoptosis Susceptibility Antibody (8O505)

Rating icon 还可以
Anti-Cellular Apoptosis Susceptibility Antibody (8O505)
产品编号 TMAC-00813 别名 XPO2_HUMAN, XPO2, XPO 2, MGC130037, MGC130036, MGC117283, Importin-alpha re-exporter, Importin alpha re exporter, Exportin-2, Exportin2, Exportin 2, Exp2, Exp 2, CSE1L, CSE1 chromosome segregation 1 like protein, CSE1 chromosome segregation 1 like (yeast), CSE1 chromosome segregation 1 like, CSE1, CSE 1L, CSE 1 chromosome segregation 1 like protein, CSE 1 chromosome segregation 1 like, CSE 1, Chromosome segregation gene CSE1, Chromosome segregation 1-like protein, Chromosome segregation 1 like protein, Chromosome segregation 1 Like, Chromosome segregation 1 (yeast homolog) like, Cellular apoptosis susceptibility protein, CAS

Anti-Cellular Apoptosis Susceptibility Antibody (8O505) 是一种 Rabbit 抗体，靶向 Cellular Apoptosis Susceptibility。Anti-Cellular Apoptosis Susceptibility Antibody (8O505) 可用于 WB,ICC,IF,IHC,FCM。

规格价格库存数量
50 μL
¥ 1,495
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100 μL
¥ 2,495
5日内发货
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产品介绍

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产品描述
Anti-Cellular Apoptosis Susceptibility Antibody (8O505) is a Rabbit antibody targeting Cellular Apoptosis Susceptibility. Anti-Cellular Apoptosis Susceptibility Antibody (8O505) can be used in WB,ICC,IF,IHC,FCM.
别名XPO2_HUMAN, XPO2, XPO 2, MGC130037, MGC130036, MGC117283, Importin-alpha re-exporter, Importin alpha re exporter, Exportin-2, Exportin2, Exportin 2, Exp2, Exp 2, CSE1L, CSE1 chromosome segregation 1 like protein, CSE1 chromosome segregation 1 like (yeast), CSE1 chromosome segregation 1 like, CSE1, CSE 1L, CSE 1 chromosome segregation 1 like protein, CSE 1 chromosome segregation 1 like, CSE 1, Chromosome segregation gene CSE1, Chromosome segregation 1-like protein, Chromosome segregation 1 like protein, Chromosome segregation 1 Like, Chromosome segregation 1 (yeast homolog) like, Cellular apoptosis susceptibility protein, CAS
Ig Type
IgG
交叉反应
Human,Mouse,Rat
验证活性
1. Western blot analysis of Cellular Apoptosis Susceptibility on different lysates using anti-Cellular Apoptosis Susceptibility antibody at 1/500 dilution.Positive control: Lane 1: Mouse testis, Lane 2: SiHa, Lane 3: SK-BR-3, Lane 4: PC-3M.
2. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-Cellular Apoptosis Susceptibility antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-Cellular Apoptosis Susceptibility antibody. Counter stained with hematoxylin.
4. ICC staining Cellular Apoptosis Susceptibility in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
5. ICC staining Cellular Apoptosis Susceptibility in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
6. ICC staining Cellular Apoptosis Susceptibility in SH-SY5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
7. Flow cytometric analysis of LOVO cells with Cellular Apoptosis Susceptibility antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody.
应用
WB
ICC
IF
IHC
FCM
推荐剂量
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200; FCM: 1:50-100
抗体种类
Monoclonal
宿主来源Rabbit
构建方式Recombinant Antibody
纯化方式ProA affinity purified
性状Liquid
缓冲液1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
研究背景Cellular apoptosis susceptibility protein (CAS), also called Exportin 2, is a 971 amino acid member of the CSE1 family. CAS mediates Importin α re-export from the nucleus to the cytoplasm after import substrates have been released into the nucleoplasm. In the nucleus, CAS binds cooperatively to Importin α and to the GTPase Ran in its GTP-bound (active) form. This complex binds to nucleoporins as it docks to the nuclear pore complex. Once in the cytoplasm, the complex dissociates and Importin α is released and CAS returns to the nuclear compartment and the process begins anew. CAS can be detected highly in proliferating cells. Three isoforms of CAS have been named due to alternative splicing. Isoform 1 is the full length, 971 amino acid protein. Isoform 2 contains an alternative sequence for amino acids 190-195 and is missing amino acids 196-971. Isoform 3 contains an alternative sequence for amino acids 943-945 and is missing amino acids 946-971.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein
Uniprot ID
P55060
化学信息
分子量Theoretical: 110 kDa.
存储&运输
储存方式Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.

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