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Anti-MARVELD1 Polyclonal Antibody

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货号 TMAB-08619

Anti-MARVELD1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MARVELD1。Anti-MARVELD1 Polyclonal Antibody 可用于 WB。

Anti-MARVELD1 Polyclonal Antibody

Anti-MARVELD1 Polyclonal Antibody

一键复制产品信息
Rating icon 还可以
货号 TMAB-08619

Anti-MARVELD1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MARVELD1。Anti-MARVELD1 Polyclonal Antibody 可用于 WB。

规格价格库存数量
50 μL
¥ 1,175
5日内发货
100 μL
¥ 1,965
5日内发货
200 μL
¥ 2,780
5日内发货
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产品介绍


生物活性
产品描述
Anti-MARVELD1 Polyclonal Antibody is a Rabbit antibody targeting MARVELD1. Anti-MARVELD1 Polyclonal Antibody can be used in WB.
Ig Type
IgG
反应种属
Mouse (predicted:Human,Rabbit)
应用WB
推荐剂量
WB: 1:500-2000
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Cell membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton. Nucleus. Note=Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization.
组织特异性Widely expressed in normal tissues. Down-regulated in multiple primary tumors.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
抗原信息
免疫原
KLH conjugated synthetic peptide: human MARVELD1
抗原种属
Human
基因名称
MARVELD1
基因ID
蛋白名称
MARVEL domain-containing protein 1
Uniprot ID
功能
Microtubule-associated protein that exhibits cell cycle-dependent localization and can inhibit cell proliferation and migration
化学信息
分子量Theoretical: 19 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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