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Anti-MARVELD1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MARVELD1。Anti-MARVELD1 Polyclonal Antibody 可用于 WB。
Anti-MARVELD1 Polyclonal Antibody 是一种 Rabbit 抗体,靶向 MARVELD1。Anti-MARVELD1 Polyclonal Antibody 可用于 WB。
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 50 μL | ¥ 1,175 | 5日内发货 | |
| 100 μL | ¥ 1,965 | 5日内发货 | |
| 200 μL | ¥ 2,780 | 5日内发货 |
| 产品描述 | Anti-MARVELD1 Polyclonal Antibody is a Rabbit antibody targeting MARVELD1. Anti-MARVELD1 Polyclonal Antibody can be used in WB. |
| Ig Type | IgG |
| 反应种属 | Mouse (predicted:Human,Rabbit) |
| 应用 | WB |
| 推荐剂量 | WB: 1:500-2000 |
| 抗体种类 | Polyclonal |
| 宿主来源 | Rabbit |
| 亚细胞定位 | Cell membrane; Multi-pass membrane protein. Cytoplasm, cytoskeleton. Nucleus. Note=Observed in the nucleus and at the perinuclear region during interphase, but localizes at the mitotic spindle and midbody at metaphase. A significant fraction of MARVELD1 translocates to the plasma membrane during anaphase or upon microtubule depolymerization. |
| 组织特异性 | Widely expressed in normal tissues. Down-regulated in multiple primary tumors. |
| 构建方式 | Hybridoma Polyclonal Antibody |
| 纯化方式 | Protein A purified |
| 性状 | Liquid |
| 缓冲液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 浓度 | 1mg/ml |
| 研究背景 | MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression, suggesting that loss of MARVELD1 expression may contribute to tumorgenicity. |
| 免疫原 | KLH conjugated synthetic peptide: human MARVELD1 |
| 抗原种属 | Human |
| 基因名称 | MARVELD1 |
| 基因ID | |
| 蛋白名称 | MARVEL domain-containing protein 1 |
| Uniprot ID | |
| 功能 | Microtubule-associated protein that exhibits cell cycle-dependent localization and can inhibit cell proliferation and migration |
| 分子量 | Theoretical: 19 kDa. |
| 储存方式 | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| 运输方式 | Shipping with blue ice. |
| 存储 | store at low temperature | -20°C for 1 year |