Name: AXL Protein, Human, Recombinant (His & Avi)
Brand: TargetMol
SKU: TMPK-00407
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

5 μg

¥ 178

6-8日内发货

10 μg

¥ 268

6-8日内发货

20 μg

¥ 418

5日内发货

50 μg

¥ 797

5日内发货

100 μg

¥ 1,320

5日内发货

200 μg

¥ 2,390

5日内发货

500 μg

¥ 5,330

5日内发货

生物活性

产品描述	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers. AXL Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 48.7 kDa and the accession number is P30530-1.
生物活性	Immobilized Human AXL, His Tag at 2μg/ml (100μl/well) on the plate. Dose response curve for Anti-AXL Antibody, hFc Tag with the EC50 of 15.5ng/ml determined by ELISA.
研究背景	Axl, a member of the TAM (Tyro3, Axl, Mer) family, and its inhibitors can specifically break the kinase signaling nodes, allowing advanced patients to regain drug sensitivity with improved therapeutic efficacy. Overexpression and activation of Axl receptor tyrosine kinase have been widely accepted to promote cell proliferation, chemotherapy resistance, invasion, and metastasis in several human cancers, such as lung, breast, and pancreatic cancers.
种属	Human
表达系统	HEK293 Cells
标签	C-His-Avi
蛋白编号	P30530-1
蛋白构建	Ala26-Pro449
蛋白纯度	> 95% as determined by Tris-Bis PAGE; > 95% as determined by SEC-HPLC
蛋白性状	Lyophilized powder
缓冲液	Lyophilized from a solution filtered through a 0.22 μm filter, containing PBS (pH 7.4). Typically, 8% trehalose is incorporated as a protective agent before lyophilization.
复溶方法	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.
别名	UFO, Tyro7, JTK11, EC 2.7.10.1, EC 2.7.10, AXL oncogene, Axl, ARK, AI323647
内毒素	< 1 EU/μg by the LAL method.

化学信息

分子量	48.7 kDa (predicted). Due to glycosylation, the protein migrates to 70-80 kDa based on Tris-Bis PAGE result.

储存&溶解度

运输方式	In general, Lyophilized powders are shipping with blue ice.
存储	It is recommended to store recombinant proteins at -20°C to -80°C for future use. Lyophilized powders can be stably stored for over 12 months, while liquid products can be stored for 6-12 months at -80°C. For reconstituted protein solutions, the solution can be stored at -20°C to -80°C for at least 3 months. Please avoid multiple freeze-thaw cycles and store products in aliquots.

AXL Protein, Human, Recombinant (His & Avi)

AXL Protein, Human, Recombinant (His & Avi)

产品介绍

计算器

剂量转换

引用文献

技术支持

关键词