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顶部产品介绍偶联与修饰抗原信息储存和溶解信息计算器

Anti-Cystatin C Antibody (6I425)

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货号 TMAY-03722

别名 cystatin C

Anti-Cystatin C Antibody (6I425) 是一种 Rabbit 抗体，靶向 Cystatin C。Anti-Cystatin C Antibody (6I425) 可用于 ELISA。

Anti-Cystatin C Antibody (6I425)

Anti-Cystatin C Antibody (6I425)

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货号 TMAY-03722 别名 cystatin C

Anti-Cystatin C Antibody (6I425) 是一种 Rabbit 抗体，靶向 Cystatin C。Anti-Cystatin C Antibody (6I425) 可用于 ELISA。

规格价格库存数量
100 μL
¥ 2,284
5日内发货
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产品介绍

生物活性
产品描述
Anti-Cystatin C Antibody (6I425) is a Rabbit antibody targeting Cystatin C. Anti-Cystatin C Antibody (6I425) can be used in ELISA.
别名cystatin C
Ig Type
Rabbit IgG
克隆号
6I425
反应种属
Rat
特异性
Rat Cystatin C
Has cross-reactivity in ELISA with
Mouse CST3
Human CST3
应用ELISA
推荐剂量
ELISA: 1:5000-1:10000
抗体种类
Monoclonal
宿主来源Rabbit
构建方式This antibody was obtained from a rabbit immunized with purified, recombinant Rat Cystatin C / CST3 (rR Cystatin C / CST3; TMPY-02056; P14841-1; Met1-Ala140).
纯化方式Protein A
性状Liquid
缓冲液0.2 μm filtered solution in PBS
研究背景Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal function, particularly to detect small reductions in glomerular filtration rate. The mature, active form of human cystatin C is a single non-glycosylated polypeptide chain consisting of 120 amino acid residues, with a molecular mass of 13,343-13,359 Da, and containing four characteristic disulfide-paired cysteine residues. Cystatin C is a low-molecular-weight protein that has been proposed as a marker of renal function that could replace creatinine. Indeed, the concentration of Cystatin C is mainly determined by glomerular filtration and is particularly of interest in clinical settings where the relationship between creatinine production and muscle mass impairs the clinical performance of creatinine. Since the last decade, numerous studies have evaluated its potential use in measuring renal function in various populations. More recently, other potential developments for its clinical use have emerged. In almost all the clinical studies, Cystatin C demonstrated a better diagnostic accuracy than serum creatinine in discriminating normal from impaired kidney function, but controversial results have been obtained by comparing this protein with other indices of kidney disease, especially serum creatinine-based equations, such as early atherosclerosis, Alzheimer's dementia, vascular aneurysms, hyperhomocysteinaemia and other neurodegenerative diseases. Cystatin C could be a useful clinical tool to identify HIV-infected persons. In addition, its expression is up-regulated in malignance of certain tumor progression.
偶联与修饰
偶联
Unconjugated
抗原信息
免疫原
Recombinant Protein: Rat Cystatin C / CST3 protein (TMPY-02056)
抗原种属
Rat
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
运输方式Shipping with blue ice.

计算器

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